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The following drugs can interact with potassium bicarbonate. Tell your doctor if you are using any of these:

• digoxin (Lanoxin);

• an ACE inhibitor such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik);

• a beta-blocker such as atenolol (Tenormin), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), sotalol (Betapace), timolol (Blocadren);

• a diuretic (water pill) such as amiloride (Midamor, Moduretic), chlorothiazide (Diuril, others), hydrochlorothiazide (Hydrodiuril, HCTZ, others), indapamide (Lozol), metolazone (Zaroxolyn), spironolactone (Aldactone, Aldactazide), or triamterene (Dyrenium, Dyazide, Maxzide);

• aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), etodolac (Lodine), indomethacin (Indocin), ketoprofen (Orudis),, and others; or

• a steroid such as prednisone (Deltasone, Orasone), hydrocortisone (Cortef, Hydrocortone), dexamethasone (Decadron, Hexadrol), and others.

This list is not complete and there may be other drugs that can interact with potassium bicarbonate or affect your condition. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using potassium bicarbonate and call your doctor at once if you have any of these serious side effects:

• confusion;

• uneven heartbeat;

• unusual tiredness, weakness, heavy feeling in your legs;

• severe stomach pain cramping; or

• black, bloody, or tarry stools.

Less serious side effects may include:

• nausea, vomiting, diarrhea, or upset stomach;

• a rash;

• slight tingling in the hands or feet; or

• anxiety.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.