• Basic Info
• Top Questions
• Clinical Info
• Interactions

Before you receive oxaliplatin, tell your doctor if you also take a blood thinner such as warfarin (Coumadin).

There may be other drugs that can interact with oxaliplatin. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Some people receiving a oxaliplatin injection have had a reaction to the infusion within minutes after the medicine is injected into the vein. Tell your caregiver right away if you feel short of breath, confused, sweaty, itchy, or have diarrhea, chest pain, warmth or redness in your face, or feel like you might pass out.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

• numbness or tingly feeling in your hands, feet, throat, and around your mouth;

• numbness or burning pain that interferes with daily activities;

• increased sensitivity to cold temperatures and cold objects;

• jaw or chest tightness, eye pain, strange feeling in your tongue, problems with speech or swallowing;

• fever, diarrhea, vomiting, chills, body aches, flu symptoms, sudden cough;

• increased thirst, dry mouth, urinating less than usual;

• easy bruising or bleeding, unusual weakness; or

• white patches or sores inside your mouth or on your lips.

Less serious side effects may include:

• nausea, stomach pain, loss of appetite;

• diarrhea, constipation;

• tired feeling;

• hair loss;

• decreased taste sensation;

• muscle pain;

• headache;

• sleep problems (insomnia);

• swelling; or

• back pain.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.