Octreotide should not be used at the same time as cyclosporine (Neoral,
Sandimmune, Gengraf). Talk to your doctor before using octreotide if you are using
cyclosporine.
Before using octreotide, tell your doctor if you are taking any of the following medicines:
bromocriptine (Parlodel);
diabetes medication such as insulin, glipizide (Glucotrol),
glyburide (Diabeta, Micronase), tolbutamide (Orinase), metformin (Glucophage), pioglitazone
(Actos), rosiglitazone (Avandia), and others;
medicine for heart disease or high blood pressure; or
a diuretic (water pill).
This list is not complete and there may be other drugs that can interact
with octreotide. Tell your doctor about all the prescription and over-the-counter medications you
use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors.
Do not start using a new medication without telling your doctor.
Stop using octreotide and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face,
lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
slow or irregular heartbeats;
gallbladder problems (stomach pain);
pancreatitis (pain in the upper stomach or back, nausea,
vomiting, fever, bloating, yellowing of the skin or eyes);
thyroid problems (may be detected by blood tests);
low blood sugar (headache, confusion, drowsiness,
weakness, dizziness, fast heartbeat, sweating, tremor, nausea); or
high blood sugar (increased thirst and urination; flushed or
dry skin; drowsiness).
Less serious side effects may include:
nausea or vomiting;
diarrhea;
mild stomach pain or gas;
constipation; or
pain or irritation where you injected the medication.
This is not a complete list of side effects and others may occur. Tell
your doctor about any unusual or bothersome side effect.
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