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Before receiving norepinephrine, tell your doctor if you are using any of the following drugs:

• blood pressure medications;

• an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate); or

• an antidepressant such as amitriptyline (Elavil, Etrafon), amoxapine (Ascendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), or trimipramine (Surmontil).

If you are using any of these drugs, you may not be able to receive norepinephrine, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect norepinephrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers at once if you have any of these serious side effects:

• muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, nausea with vomiting;

• fast, slow, or uneven heart rate;

• blue lips or fingernails, mottled skin;

• urinating less than usual or not at all;

• irritation of the skin or vein where the medicine is injected;

• sudden numbness or weakness, especially on one side of the body; or

• sudden headache, confusion, problems with vision, speech, or balance.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.