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• Interactions

There may be other drugs that can interact with mesalamine rectal. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using mesalamine rectal and call your doctor at once if you have severe stomach pain, cramping, fever, headache, and bloody diarrhea.

Less serious side effects may include:

• mild nausea, vomiting, stomach cramps, diarrhea, gas;

• fever, sore throat, or other flu symptoms;

• rectal pain, constipation;

• headache or dizziness;

• tired feeling; or

• skin rash.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.