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• Interactions

It is not known whether leuprolide will interact with other medicines. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

If you experience any of the following serious side effects, stop using leuprolide and seek emergency medical attention or contact your doctor immediately:

• an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);

• difficulty urinating;

• bone pain; or

• numbness, tingling, or weakness in the legs or arms.

Other, less serious side effects may be more likely to occur. Talk to your doctor if you experience

• hot flashes or sweating;

• decreased libido or impotence;

• lack of energy;

• depression;

• breast enlargement;

• nausea or vomiting;

• constipation;

• weakness;

• dizziness;

• headache; or

• redness, burning, itching, or swelling at the injection site.

Any woman using leuprolide who experiences menstrual bleeding during treatment should contact her healthcare provider.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.