Do not receive any vaccination that involves the use of a live vaccine while using etanercept,
without first talking to your doctor. Etanercept may affect the immune system and a live vaccine could
possibly result in an infection.
Before using etanercept, talk to your doctor if you are using anakinra (Kineret). You may not
be able to use etanercept, or you may require a dosage adjustment or special monitoring during
treatment.
It is not known if other drugs interact with etanercept. Talk to your doctor and pharmacist
before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal
products.
In rare cases, etanercept has caused serious blood problems. Notify your doctor
immediately if you develop persistent fever; extreme or unusual fatigue; unexplained or prolonged
bruising or bleeding; black, bloody or tarry stools; fever or chills; or signs of infection such as sore
throat or pale skin. These symptoms may be signs of blood problems.
If you experience and of the following serious side effects, stop using etanercept, and seek
emergency medical attention or contact your doctor immediately:
an allergic reaction (difficulty breathing; closing of the throat;
swelling of the lips, tongue, or face; or hives);
new or worsening neurologic symptoms such as worsening
muscle pain, weakness or numbness; visual disturbances; seizures; or
depression or other psychological changes.
If you develop any of the symptoms of tuberculosis (a dry cough that
doesn't go away, weight loss, fever, night sweats) call your doctor. You will need to be examined for
TB and have a skin test.
You may have reactions where the injection is given. These reactions are usually mild and can
include redness, rash, swelling, itching, or bruising. These reactions usually go away within 3 to 5 days.
If you have pain, redness or swelling around the injection site that doesn't go away or gets worse, call
your doctor immediately.
Other less serious side effects may be more likely to occur. Continue to use etanercept and
notify your doctor if you experience
a headache; or
sinus infection.
Side effects other than those listed here may also occur. Talk to your doctor
about any side effect that seems unusual or that is especially bothersome.
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