Talk to your doctor before taking any medicine for pain, arthritis, fever, or swelling. This includes aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), indomethacin, piroxicam (Feldene), nabumetone (Relafen), etodolac (Lodine), and others. Taking any of these drugs with escitalopram may cause you to bruise or bleed easily.
Before taking escitalopram, tell your doctor if you are using any of the following medicines:
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carbamazepine (Carbatrol, Tegretol);
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cimetidine (Tagamet);
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lithium (Lithobid, Eskalith);
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a blood thinner such as warfarin (Coumadin);
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any other antidepressants such as amitriptyline (Elavil), citalopram (Celexa), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Tofranil), nortriptyline (Pamelor), paroxetine (Paxil), or sertraline (Zoloft); or
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almotriptan (Axert), frovatriptan (Frova), sumatriptan (Imitrex), naratriptan (Amerge), rizatriptan (Maxalt), or zolmitriptan (Zomig).
If you are using any of these drugs, you may not be able to use escitalopram, or you may need dosage adjustments or special tests during treatment.
There may be other drugs not listed that can affect escitalopram. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Get emergency medical help if you have any of these
Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.
Call your doctor at once if you have any of these serious side effects:
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seizure (convulsions);
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tremors, shivering, muscle stiffness or twitching;
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problems with balance or coordination; or
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agitation, confusion, sweating, fast heartbeat.
Other less serious side effects are more likely to occur, such as:
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feeling nervous, restless, or unable to sit still;
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headache, trouble concentrating;
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drowsiness, dizziness;
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sleep problems (insomnia);
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nausea, diarrhea, heartburn;
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weight changes;
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decreased sex drive, impotence, or difficulty having an orgasm; or
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dry mouth, ringing in your ears.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

