• Basic Info
• Top Questions
• Clinical Info
• Interactions

Do not take codeine with other narcotic pain medications, sedatives, tranquilizers, muscle relaxers, or other medicines that can make you sleepy or slow your breathing. Dangerous side effects may result.

There may be other drugs that can interact with codeine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• shallow breathing, slow heartbeat;

• feeling light-headed, fainting;

• confusion, agitation, hallucinations, unusual thoughts or behavior;

• seizure (convulsions); or

• problems with urination.

Less serious side effects include:

• feeling dizzy or drowsy;

• nausea, vomiting, constipation;

• sweating;

• headache;

• trouble sleeping (insomnia);

• loss of interest in sex;

• dry mouth;

• blurred vision; or

• mild skin rash.

This list is not complete and other side effects may occur. Tell your doctor about any unusual or bothersome side effect.