• Basic Info
• Top Questions
• Interactions

Before taking this medication, tell your doctor if you are using any of the following drugs:

• a diuretic (water pill), or blood pressure medication;

• medication to treat irritable bowel syndrome;

• bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol);

• aspirin or salicylates (such as Disalcid, Doan's Pills, Dolobid, Salflex, Tricosal, and others); or

• antidepressant medications such as amitriptyline (Elavil, Etrafon), bupropion (Wellbutrin, Zyban), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Janimine, Tofranil), paroxetine (Paxil), sertraline (Zoloft), others.

This list is not complete and there may be other drugs that can interact with chlorpheniramine and dextromethorphan. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

• fast, pounding, or uneven heartbeat;

• slow, shallow breathing;

• severe dizziness, anxiety, restless feeling, or nervousness;

• confusion, hallucinations, unusual thoughts or behavior;

• urinating less than usual or not at all; or

• easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms.

Less serious side effects may include:

• dry mouth;

• nausea, stomach pain, constipation;

• blurred vision;

• dizziness, drowsiness;

• problems with memory or concentration;

• ringing in your ears; or

• restlessness or excitability (especially in children).

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.