Although capsaicin topical is unlikely to affect medicines taken by mouth, talk to your
doctor before using capsaicin topical if you are taking any other prescription medicines. You may
not be able to use capsaicin topical, or you may require a dosage adjustment or special monitoring.
Avoid using other topical products on the treated area without first talking to your doctor.
Other topical products may affect the absorption or effectiveness of capsaicin topical.
Drugs other than those listed here may also interact with capsaicin topical. Talk to your
doctor and pharmacist before taking or using any other prescription or over-the-counter medicines,
including vitamins, minerals, and herbal products.
Stop using capsaicin topical and seek emergency medical attention or contact your
doctor immediately if you experience any of the following rare but serious side effects:
an allergic reaction (difficulty breathing; closing of the throat;
swelling of the lips, tongue, or face; or hives); or
severe skin irritation or skin ulceration (skin wound).
Other less serious side effects may be more likely to occur. Continue to
use capsaicin topical and talk to your healthcare provider if you experience
mild irritation, redness, or burning at the application site.
Side effects other than those listed here may also occur. Continue to use
capsaicin topical and talk to your doctor about any side effect that seems unusual or that is
especially bothersome.