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Many other drugs may increase the side effects of atropine. Before taking this medication, tell your doctor if you are taking any of the following medicines:

• amantadine (Symmetrel);

• quinidine (Quinaglute, Cardioquin, Quinora, Quinidex);

• antihistamines such as diphenhydramine (Benadryl, many others), brompheniramine (Dimetapp, Bromphen, many others), triprolidine (Actifed, others), and chlorpheniramine (Chlor-Trimeton, others), which are found in many over-the-counter and prescription cough, cold, and allergy medications;

• decongestants and appetite suppressants such as phenylpropanolamine (Dexatrim, others), phenylephrine (Neo-Synephrine, others), and pseudoephedrine (Sudafed, others), which are also found in many over-the-counter and prescription products;

• phenothiazines such as chlorpromazine (Thorazine) and prochlorperazine (Compazine);

• other commonly used phenothiazines, including fluphenazine (Prolixin), mesoridazine (Serentil), perphenazine (Trilafon), thioridazine (Mellaril), trifluoperazine (Stelazine), and promazine (Sparine);

• tricyclic antidepressants such as amitriptyline (Elavil, Endep), doxepin (Sinequan) and nortriptyline (Pamelor); or

• other commonly used tricyclic antidepressants, including amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), imipramine (Tofranil), protriptyline (Vivactil), and trimipramine (Surmontil).

Atropine may increase the level of digoxin (Lanoxin, Lanoxicaps) in your blood. Tell your doctor if you are taking digoxin so that your digoxin levels can be monitored and changes in your dosage can be made if necessary.

Drugs other than those listed here may also interact with atropine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

If you experience any of the following serious side effects, stop taking atropine and seek emergency medical attention:

• an allergic reaction (swelling of your lips, tongue, or face, difficulty breathing, closing of your throat, or hives);

• an irregular or fast heart rate;

• rash or flushing; or

• eye pain.

Other, less serious side effects may be more likely to occur. Continue to take atropine and talk to your doctor if you experience

• headache, dizziness or lightheadedness;

• weakness or nervousness;

• blurred vision, large pupils, or sensitivity of the eyes to bright light;

• nausea, bloating, heartburn, or constipation;

• changes in taste;

• difficulty urinating;

• decreased sweating; or

• nasal congestion, stuffiness, or a dry mouth.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.