Generic Name: APAP/dichloralphenazone/isometheptene

Do not take acetaminophen, dichloralphenazone, and isometheptene if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. Dangerous side effects could result.

Dichloralphenazone may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine unless your doctor approves.

Many other medicines contain acetaminophen, especially over-the-counter pain, fever, cold, and allergy medications. Too much acetaminophen can be very dangerous.

Drugs other than those listed here may also interact with acetaminophen, dichloralphenazone, and isometheptene. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

If you experience any of the following serious side effects, stop taking acetaminophen, dichloralphenazone, and isometheptene and seek emergency medical attention:

• an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

• liver damage (yellowing of the skin or eyes, abdominal pain); or

• blood problems (easy or unusual bleeding or bruising).

These side effects are very rare and are not likely to occur during proper treatment with acetaminophen, dichloralphenazone, and isometheptene.

Other, less serious side effects may be more likely to occur. Continue to take acetaminophen, dichloralphenazone, and isometheptene and talk to your doctor if you experience

• nausea;

• dizziness, tiredness, or lightheadedness; or

• a rash.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.