Do not receive "live" vaccines during treatment with anakinra without first talking to your
doctor. Administration of a live vaccine may result in an inadequate immune response or infection.
Before using anakinra, talk to your doctor if you are taking
etanercept (Enbrel);
infliximab (Remicade);
adalimumab (Humira); or
a medicine that may decrease the effects of the immune
system.
You may not be able to use anakinra, or you may require a dosage
adjustment or special monitoring during treatment if you are taking any of the medicines listed above.
Drugs other than those listed here may also interact with anakinra. Talk to your doctor and
pharmacist before taking any prescription or over-the-counter medicines, including herbal products.
If you experience an allergic reaction (difficulty breathing; closing of the throat; swelling of
your lips, tongue, or face; or hives), stop using anakinra, and seek emergency medical attention.
In rare cases, people receiving anakinra have developed serious infections. Notify your
doctor immediately if you develop a fever, flu-like symptoms, or any other sign of infection.
Other less serious side effects may be more likely to occur. Continue to use anakinra and notify
your doctor if you experience
nausea or diarrhea;
a headache;
sinus irritation or infection; or
redness, bruising, pain, or swelling at the injection site.
Side effects other than those listed here may also occur. Talk to your doctor
about any side effect that seems unusual or that is especially bothersome.
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