Antacids, supplements, or medicines that contain aluminum, calcium, magnesium, or
other minerals can interfere with how your body absorbs alendronate. If you use these other
medicines, do not that take them for at least 30 minutes after taking an alendronate tablet.
Before using alendronate, tell your doctor if you also use aspirin or other NSAIDs
(non-steroidal anti-inflammatory drugs) such as celecoxib (Celebrex), diclofenac (Voltaren),
diflunisal (Dolobid), ibuprofen (Motrin, Advil), indomethacin, ketoprofen (Orudis), ketorolac
(Toradol), naproxen (Aleve, Naprosyn), piroxicam (Feldene), and others.
There may be other drugs that can affect alendronate. Tell your doctor about all the
prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal
products, and drugs prescribed by other doctors. Do not start using a new medication without
telling your doctor.
Get emergency medical help if you have any of these signs of an allergic
reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using alendronate and call your doctor at once if you have any of these serious
side effects:
chest pain;
difficulty or pain when swallowing;
pain or burning under the ribs or in the back;
new or worsening heartburn;
severe joint, bone, or muscle pain; or
jaw pain, numbness, or swelling.
Continue using alendronate and talk with your doctor if you have any
of these less serious side effects:
mild heartburn or stomach upset;
diarrhea, gas, or constipation;
joint pain or swelling;
swelling in your hands or feet;
back pain; or
dizziness, weakness, or headache.
Side effects other than those listed here may also occur. Talk to your
doctor about any side effect that seems unusual or that is especially bothersome.
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