• Basic Info
• Top Questions
• Clinical Info
• Interactions

Before taking this medication, tell your doctor if you are taking any of the following medicines:

• cyclosporine (Sandimmune). Cyclosporine may have more side effects if it is taken with acetazolamide.

• primidone (Mysoline). Primidone may not be as effective if it is taken with acetazolamide, and seizure control may be reduced.

• diflunisal (Dolobid). Diflunisal may increase both the activity and the side effects of acetazolamide.

• aspirin, salsalate (Disalcid, Salflex, Salsitab, others), choline salicylate (Arthropan), magnesium salicylate (Doan's, Magan, Mobidin), and other aspirin-like products (salicylates). These medicines may also interact with acetazolamide, and special monitoring of your therapy may be necessary.

• lithium (Lithobid, Eskalith, others). Acetazolamide may decrease the level of lithium in your blood. Special monitoring or a dosage adjustment may be necessary.

Drugs other than those listed here may also interact with acetazolamide. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

If you experience any of the following serious side effects, stop taking acetazolamide and seek emergency medical attention:

• an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

• a sore throat or a fever;

• unusual bleeding or bruising;

• side or groin pain;

• tingling or tremors in your hands or feet; or

• a rash.

Other, less serious side effects may be more likely to occur. Continue to take acetazolamide and talk to your doctor if you experience

• decreased appetite, nausea, vomiting, constipation, diarrhea, or changes in taste;

• drowsiness, dizziness, fatigue, or weakness;

• nervousness or mild tremor;

• headache or confusion;

• increased sensitivity of the skin to sunlight;

• worsening gout;

• loss of blood sugar control (if you are diabetic);

• ringing in your ears or hearing problems; or

• changes in your vision.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.