Figure 63-10. Meta-analysis of randomized controlled i...
Figure 63-10. Meta-analysis of randomized controlled intervention trials. The difference in systolic blood pressure between placebo and active treatment or between less intense and more intense treatment for hypertension is plotted against the relative risk of fatal or nonfatal cardiovascular events. Within the 95% confidence intervals used in this regression analysis, the reduction in cardiovascular mortality afforded by the various antihypertensive treatment regimens in these large numbers of trials is linearly related to the magnitude of blood pressure lowering.