Located in the pancreas, the pancreatic vein is responsible for draining the pancreas into the superior mesenteric and splenic veins. It contributes a significant role of the pancreas since this gland has a diverse set of functions in digestion, metabolism, absorption, as well as in the sustenance of nutrients. In executing its function of draining the pancreas, it also consists of other small vessels in draining the body up to the tail of the gland. This kind of function helps out the pancreas since this gland serves as storage of digestive enzymes. With the sensitive function of the pancreas, recent studies show a significant high prevalence of pancreatic diseases that are fatal to the human body such as deadly cancers. The participation of the pancreatic vein in draining the pancreas body and tail to the mesenteric and splenic veins shares an attribute in the occurrence of these diseases and is being highly monitored by the medical field. These types of diseases eventually called the immediate attention in order to discover different treatments in overcoming such dreadful diseases and fight against the high mortality rate.