Medial globus pallidus

The medial globus pallidus is the term used for an output nuclei from the basal ganglia. The basal ganglia are vast nuclei collections that adjust and change movement every minute. Motor cortex transmits information directly to the basal ganglia, along with the cerebellum. Through the thalamus, the ganglia also responds back with information. The basal ganglia produces inhibitory output, while the cerebellum's output is excitatory. Alongside the pallidus, the other type of output nuclei is the substantia nigra pars reticulata, which is a section of the substantia nigra, a midbrain structure. Another common name for the pallidus is substantia innominata, which means the great unknown. The medial globus pallidus consists of neurons that contain gamma-aminobutyric acid, which is also known as GABA. These neurons send axons to various nuclei from the dorsal thalamus, and then over to the pedunculopontine (of the brainstem) and centromedian (of the thalamus) nuclei. The pallidus is close to the nucleus subthalamicus, the putamen and the mesencephalon.
Written and medically reviewed by the Healthline Editorial Team
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In Depth: Medial globus pallidus

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