The cochlear labyrinth is the portion of the inner ear that contains the cochlear duct and the perilymphatic space. The cochlear labyrinth is a fluid filled membrane that helps in the detection of sound. The cochlear labyrinth is primarily used to sense lower frequencies. A recent study has shown that the volume of the cochlear labyrinth has a strong negative correlation with the high frequency hearing limit. The cochlear labyrinth's fluid is called endolymph. Endolymph is low in sodium and high in potassium, which allows it to maintain an ionic composition necessary to the functioning of auditory and vestibular cells. The cochlear labyrinth is one of the most sensitive structures to vertebrobasilar ischemic stroke. Low frequency hearing loss may result from the irreversible deterioration of the cochlea. Studies also suggest that vertigo may be a manifestation of transient ischemia in the vertebrobasilar circulation. Corticosteroids function by suppressing the system mediated inflammatory immune response in the cochlea. The drug reacts with intracellular glucocorticoid receptors, which are most highly concentrated in the cochlear labyrinth.
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In Depth: Cochlear labyrinth