Vagus Nerve Stimulation sends intermittent signals to the brain that help to balance our emotions.
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Question: How does vagus nerve stimulation trest depression? Mark S. George: Fundamentally, we don't know how it treats depression and fundamentally we don't know what depression is in the brain. Unfortunately, we need a lot more science research about that. we do have ideas and theories and we do know that, when someone is depressed, parts of the brain specifically kind of right in here, the base of the frontal cortex, shuts off and is not working. We know that the biggest nerve sends its information pop to that kind of emotional centre of the brain. Fundamentally, vagus nerve stimulation sends signals up to that part of the brain that's involved in regulating our gut and also controlling emotion. And somehow, the inner made in signals rewrite our system that's in imbalance. Play that works. This is the prescription pad and this is the pharmacist. so essentially, I put this over the spark where somebody has one and then I can choose different settings here, and then plug them in and well, the device itself will remember what I told it do and it will discharge fire in the way that I have. So, the way that a doctor treats someone with this a hand held device like this. So the VNS is, it's an interesting new option for treating depression. These people who had horrible depression and nothing works, a lot of people can get their lives back with it. And it's really refreshing for me as a doctor and as a scientist to see that people who would otherwise be living lives of misery at home are back in the game and they are doing good things for society and that's really wonderful. Its quiet frustrating for me, that it doesn't work in everybody and that we can't figure out in advance, who it's going to work in and that we don't understand as well as we should, how to manipulate what it does in the brain. So, I'm simultaneously glad as a clinical doctor, I'm still greedy as a scientist, that we have got so much more to do with it.

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