The Vulnerability of the Y Chromosome Video

Marianne Legato, professor of Clinical Medicine at Columbia University, talks about how the masculine chromosome is unique in its inability to repair itself, making it exceptionally prone to mutation and pollution.
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The Vulnerability of the Y Chromosome So, Y chromosome is definitely unique among all the chromosomes. Over most of its extent, it can’t exchange with its partner the X chromosome to repair its deficiencies or mutations in DNA. It’s learned to repair itself in an interesting and unique way. The issues with the Y chromosome are that they are exposed to environmental toxins because they are housed outside the body in the scrotal sack. Many millions are produced every day and, therefore, mutations are far more frequent in the Y chromosome than in the X or indeed in any of the other chromosomes. So the male drives evolutionary development because of this extraordinary proliferation of mutations that are characteristic of sperm and the Y chromosome.

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