Women with polycystic ovarian syndrome have difficulty with their fertility because they don’t ovulate regularly. So if a woman with normal hormone functioning desires of pregnancy and ovulates 12 times a year one time during each of her menstrual cycles, she has 12 opportunities a year for the egg to join the sperm. If she is anovulatory or oligo-ovulatory, meaning she doesn’t ovulate as frequently as that, she may only have three or four opportunities a year to actually achieve a pregnancy. So that is probably the main reason why women with polycystic ovarian syndrome have what we call sub-fertility or infertility.