Dr. Matava explains whether anti-rejection medication is needed if a cadaver graft is used during anterior cruciate ligament (ACL)surgery.
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No, you do not. The ACL and the cartilage and structures of that nature around the knee are considered immune-privileged and so there is not really a rejection phenomenon like you would see with a heart transplant or a lung transplant. In addition, there is not a blood supply that goes through an ACL graft, again, like a large organ would be transplanted and so, you do not have to have anti-rejection medications.