Cholesterol-fighting statin drug, brand name Crestor, reduces the risk of heart attack, stroke, and cardiovascular disease by about half in people who do not have high cholesterol.
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Rebecca Fox: It’s being held that’s a study that will change the way doctors practice medicine. Researchers reported that a cholesterol fighting Statin Drug brand name Crestor reduces the risks of heart attack, stroke and cardiovascular disease by about half. And people who do not have high cholesterol. The study founded Crestor maker after Zeneca will take nearly 18,000 men and women with elevated levels of a protein associated with heart disease. So, what is this mean for you, as use medical editor Dr. Monica to give us the details, and Dr. Mona how significant is the study? Dr. Mona: Well Rebecca it’s so significant that leading doctors especially cardiologist are saying that they know, they are going to see an increase in there patients coming in to asks that they need to be put on the set in medication like Crestor. Rebecca Fox: And that’s involve with the study to had normal cholesterol but elevated level of C reactive protein. What is C reactive protein and what is that measure? Dr. Mona: It’s interesting I didn’t graduate from medical school all that long ago, but see reactive protein or CRP as we call was barely mentions during my training and now all of the sudden it’s seems like it’s emerging it’s a bigger and bigger player not only in heart disease but in other medical conditions were inflammation is involve. C reactive protein is a protein that actually measures inflammation in the body, unfortunately for the study in heart disease patients it’s not only elevated in patients who are at risk for heart disease it’s also elevated in many conditions that cause inflammation throughout the body like Lopes, like rheumatoid arthritis it’s elevated in cancer patients. Even patients who are in contraceptive pills they can have high C reactive protein levels. Patients with diabetes, pregnant women so unfortunately it’s not a specific as we would like you to be to say, wow if it’s high that means that you are at risks for developing heart disease. It’s not specific but it’s interesting concept to say that if it’s high despite the fact that your LDL cholesterol is low then we should be treating you more aggressively to prevent strokes, prevent heart attacks and prevent other kinds of heart disease. Rebecca Fox: So who should take these medications? Dr. Mona: Well the study actually look that you set it 18,000 patients in 26 countries, it look at women over the ages of 60 men over the ages 50 because women develop heart disease as a whole later than man probably because of the hormone affect. So, because it was studied the net population and that’s really the only population that we can generalize it too. And what some of the study proponent are saying is that Crestor should be given then to people who have high levels of C reactive protein even despite affect that they’re cholesterol levels particularly the LDL cholesterol is normal or if it’s low. Now, there are some issues with all of this, firs of all Crestor is a medication called the Statin Medication which is what you mention. Statin Medications are HMG-CoA reductase inhibitors which basically mean that they block the body’s ability to make cholesterol that’s one of the reasons how they work in lowering heart disease. So, even though the study was only done using Crestor because its falls in the general class called Statins can we then extract the results of the study to all Statins despite effective not all Statins for use in the study that’s the first limit. Most sex purchasing yes, just because Crestor was studied doesn’t mean that this is your medication that will do this same thing or have the same affect. The second issue is Crestor is fairly expensive I mean, you can cost up to four or five of pill depending on where you get it. Not only that during the test for C reactive protein is expensive as well it can cost to up to $50 or more. So, you run into all these issues about wow you know we had kind of hand lowering heart disease down to a science. We look to chol
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