Learn About an Endoscopic Mucosal Resection Video

Dr. Sharmila Anandasabapathy, director of endoscopy at The Mount Sinai Hospital in New York, describes endoscopic mucosal resection. It is typically performed for Barretts esophagus, early cancer of the esophagus, or pre-cancer of the esophagus. D...
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What Is An Endoscopic Mucosal Resection? The procedure that's called Endoscopic Mucosal Resection where the abnormal lining is actually cutout through an endoscope was actually pioneered in Japan. There are several centers in the United States where this is performed, they usually centers that specialize on Barrett's esophagus and where the endoscopist have a higher level of expertise. And we do receive patients from all over the country who are interested in exploring this procedure versus either endoscopic removal of this esophagus or potentially ablation. An Endoscopic Mucosal Resection is typically performed for Barrett's esophagus with either pre-cancer what is called high-grade dysplasia or an early cancer. What is called an interamucosal adenocarcinoma, one that hasn't breached the deep layers of the esophagus? These patients are sedated for a standard endoscopic procedure. The endoscope typically is inserted through the mouth of the patient and has a small plastic cap at the end of the scope. The lining of the esophagus is pulled into the cap, a snare is basically put around the polyp that is created, and then using current and the snare the polyp or the lining of the esophagus is removed. We can do several of these at a time effectively removing several centimeters of the lining of esophagus. The procedure goes through the endoscopic mucosal layer as well as the sub mucosal layer and the specimen that is removed is central pathologist for interpretation. So, you are able to actually obtain a pathologic report of what was removed and what the patient had which is an advantage of this procedure. And the best data we have from this is actually been done in Germany, where they been doing the procedure for several years now and patients who underwent this procedure for early intramucosal cancer where noted to have the same age adjusted survival as the average German population over a five year period. So it's quite effective for the treatment of early cancer.

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