In this medical video learn how researchers inject patients with a lab version of HDL, or good cholesterol to treat heart disease.
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Jennifer Matthews: Fourteen years ago, Bob Garrison had a heart attack -- an event that led to several angioplasties and eventually to Doctor Muhammad Yasin. Dr. Muhammad Yasin: Bob was known to have coronary artery disease. He came in with what we call unstable angina or acute coronary syndrome, where he was ready to have a heart attack. Jennifer Matthews: Doctor Yasin asked Bob to participate in a clinical trial to reduce the plaque in his heart. Bob said yes. Bob Garrison: They injected a solution in my arm and you sat for about an hour, and then you left for a couple of hours, and then you came back, and they did some other things. Jennifer Matthews: To reduce years of plaque that had built up in Bob's heart, doctor Yasin injected him with a lab-produced version of HDL -- or good cholesterol. Dr. Muhammad Yasin: In the long-run, there is a reduction in the plaque size. In the short-run, I think we decrease inflammation in the artery wall. Jennifer Matthews: Those injections of HDL have the potential to reverse years of heart disease. Dr. Muhammad Yasin: This is the first time we have proved that this medication, or any medication, can cause significant reduction in the plaque size. Jennifer Matthews: Bob says he feels great and is grateful he avoided what he feared could have happened. Bob Garrison: I'm sure I would continue to have angioplasty or maybe finally open-heart surgery. Jennifer Matthews: Now, Bob's doing all he can to protect his health and his heart. This is Jennifer Matthews reporting.