Female Speaker: What is a date rape drug? Gwendolyn Fancavillo: Date rape drugs are given to you by other people to lower your inhibitions, to do things you normally wouldn't do. So alcohol could be used to do this as well, as well as three other drugs. Roofies, Rohypnol, ketamine, and GHB. Those three could be slipped into your drink be alcohol or not to make you feel drowsy, black out and go along with whatever the people want you to do that you normally wouldn't do as far as maybe being date rape or other sexual behaviors.