The Genetics Of Inflammatory ... Video Transcript

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And the behavior of that disease tends to be more of a stricturing or scarring type of disease, rather than inflammatory or fistulizing disease. In addition, patients with NOD-2 abnormalities are more likely to have a younger age of onset of the disease.

ANNOUNCER: There's also the possibility that knowledge about genetic factors in IBD may lead to prevention or a cure. But those goals remain far off, and depend on a great deal more research.

JUDY CHO, MD: We don't really understand at this point in time what the prevention of Crohn's disease may entail. But if through genetics and through the identification of additional genes we can identify a subset of individuals at high risk, we can then start thinking about prevention, which is really what families and patients care about. And so if we could identify disease at its earliest stages, if we can start identifying the earliest triggers that go wrong to cause disease, then we can start thinking about the big words: like prevention and cure.

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