Psoriasis Risk Factors | Medications and Family History
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Psoriasis Risk Factors

Overview

Highlights

  1. Psoriasis is an autoimmune condition in which your body produces skin cells too quickly, causing red, itchy, scaly skin.
  2. Scientists believe the condition can be inherited.
  3. Although the cause isn’t fully known, there are several risk factors and triggers.

Psoriasis is an autoimmune condition characterized by inflamed and scaly skin. Your body creates new skin cells in about a month, but people with psoriasis grow new skin cells in a few days. Your immune system is overactive and your body can’t shed skin cells faster than it produces them, causing skin cells to pile up and creating red, itchy, and scaly skin.

Research is still ongoing as to the cause of psoriasis, but according to the National Psoriasis Foundation, around 10 percent of people inherit one or more of the genes that could lead to it, but only 2 to 3 percent of people get the disease. This means that a combination of things have to happen for you to develop psoriasis: you have to inherit the gene and be exposed to certain external aspects.

Symptoms

Symptoms Icon

Psoriasis often appears as itchy, red patches of skin covered with silvery scales, but other symptoms include:

  • dry or cracked skin that can bleed
  • thickened, pitted, or ridged nails
  • swollen and stiff joints

Psoriasis patches can range from a few flaky spots to large scaly areas. It usually comes and goes in phases, flaring for a few weeks or months, then going away for a time or even going into full remission.

Risk Factors

Risk Factors

Several risk factors that can contribute to the development of psoriasis are described below.

Stress

While stress doesn’t cause psoriasis, it can cause an outbreak or exacerbate an existing case.

Skin Injury

Psoriasis can appear on areas of your skin where vaccinations, sunburns, scratches, or other injuries have occurred.

Medications

According to the National Psoriasis Foundation, certain medications are associated with triggering psoriasis, including:

  • lithium, which is used to treat certain mental health conditions, such as bipolar disorder, makes psoriasis worse in about half of people who have it
  • antimalarials can cause psoriasis flare-ups typically two to three weeks after you start taking the medication
  • propranolol (Inderal) is used to treat high blood pressure and it makes psoriasis worse in about 25 to 30 percent of patients
  • quinidine, used to treat types of irregular heartbeats, worsens psoriasis in some people
  • indomethacin (Tivorbex) is used to treat arthritis, and has made psoriasis worse in some cases

Viral and Bacterial Infections

Psoriasis may be more severe in patients who have a compromised immune system, including people who have AIDS, people who are undergoing chemotherapy treatment for cancer, or people with another autoimmune disorder, such as lupus or celiac disease. Children and young adults with recurring infections, such as strep throat or upper respiratory infections, are also at an increased risk of worsened psoriasis.

Family History

Having a parent with psoriasis increases your risk of developing it, and having two parents with it increases your risk even more. A parent with the disease has about a 10 percent chance of passing it down to their child. If both parents have psoriasis, there’s a 50 percent chance of passing down the trait.

Obesity

Plaques – red patches of skin with dead, white skin on top – are symptoms of all types of psoriasis and can develop in deep skin folds. Friction and sweating that occurs in deep skin folds of people with excess weight can lead to or aggravate psoriasis.

Tobacco

This study found that smoking nearly doubles a person’s chance of acquiring psoriasis. This risk increases with the number of cigarettes smoked in a day, and is also higher in women than men.

Alcohol

Research into the effects of alcohol on psoriasis is a bit muddled because smoking and drinking often go hand in hand. This study found that drinking alcohol is associated with psoriasis in men. Researchers also believe alcohol can worsen symptoms because it upsets the liver and may trigger the growth of Candida, a type of yeast that can worsen psoriasis symptoms.

Alcohol can also have dangerous side effects if mixed with certain medications used for treating psoriasis.

Cold Temperatures

People with psoriasis who live in colder climates know that winter makes symptoms worse. The extreme cold and dryness of certain weather will pull moisture from your skin, inflaming symptoms.

Race

This study shows that people with fairer complexions are typically more likely to develop psoriasis than people with a darker complexion.

Treatment

Treatment Icon

Many treatments are available to manage pain and symptoms of psoriasis. Treatments you can try at home include:

  • using a dehumidifier
  • soaking in a bath with Epsom salts
  • taking dietary supplements
  • changing your diet

Other treatments include:

  • topical creams and ointments
  • drugs to suppress your immune system
  • phototherapy, a procedure in which your skin is carefully exposed to natural or artificial ultraviolet (UV) light
  • pulsed dye laser, a process that destroys tiny blood vessels in areas around psoriasis plaques, cutting off blood flow and reducing cell growth in that area

Among the new treatments for psoriasis are oral treatments and biologics.

Outlook

Icon Outlook

The causes of psoriasis aren’t fully known, but risk factors and triggers are well documented. Researchers continue to uncover more about this condition. There may not be a cure, but there are many treatments available to manage pain and symptoms. 

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