Osteoarthritis


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3 Signs It’s Time for a Different Knee Pain Treatment

Osteoarthritis knee pain can be frustrating and unpredictable. But there's no reason to just live with the pain. In fact, there are good reasons to find another treatment sooner rather than later.

  • 1/
    Does-your-knee-pain-force-you-to-give-things-up

    Does your knee pain force you to give things up?

    You shouldn’t have to give things up due to pain. Be honest with yourself and your doctor about the effect knee pain is having on your activities.

  • 2/
    Is-knee-pain-keeping-you-from-exercising

    Is knee pain keeping you from exercising?

    Exercise is a key component of any treatment plan for osteoarthritis knee pain. If your knee pain is preventing you from exercising, that is a sign you may need to talk to your doctor about available treatment options.

  • 3/
    Are-your-current-treatments-falling-short

    Are your current treatments falling short?

    If you’ve tried exercise and over-the-counter pain relievers, and haven’t found enough knee pain relief, don’t give up. There are other options besides surgery. Talk to your doctor about the right treatment for you.

  • Ready to try something different?

    When exercise and over-the-counter pain relievers aren't enough, Synvisc-One® (hylan G-F 20), the #1 prescribed viscosupplement injection, can help provide the osteoarthritis knee pain relief you need.


    Viscosupplements add to your natural joint fluid to help lubricate the joint to keep it working smoothly and act as a shock absorber to cushion bones when you move.


    They’re different from steroid injections, which are used to reduce inflammation and relieve pain.


    Your doctor is counting on you to be honest about your pain and direct about your needs. When you’re ready to try something different be sure to ask your doctor if Synvisc-One is right for you.

  • Get-up-to-six-months

    Get up to six months of osteoarthritis knee pain relief with Synvisc-One.*

    You don’t need to be in constant pain to be ready for a different treatment.

    Receive a FREE Osteoarthritis Knee Pain Relief Info Kit to learn more about Synvisc-One today.

  • *As shown in a medical study comparing Synvisc-One to an injection of salt water.

  • Indication

    Synvisc-One® (hylan G-F 20) is indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, e.g., acetaminophen.

    Important Safety Information for Synvisc-One

    Before trying Synvisc-One, tell your doctor if you have had an allergic reaction, such as swelling of the face, tongue or throat, respiratory difficulty, rash, itching or hives to SYNVISC or any hyaluronan-based products. Should not be used in patients with an infected knee joint, skin disease or infection around the area where the injection will be given, or circulatory problems in the legs.

    Synvisc-One is only for injection into the knee, performed by a doctor or other qualified health care professional. Synvisc-One has not been tested to show pain relief in joints other than the knee. Tell your doctor if you are allergic to products from birds – such as feathers, eggs or poultry – or if your leg is swollen or infected.

    Synvisc-One has not been tested in children (≤21 years old), pregnant women or women who are nursing. You should tell your doctor if you think you are pregnant or if you are nursing a child.

    Talk to your doctor before resuming strenuous weight-bearing activities after treatment.

    The side effects sometimes seen after Synvisc-One include (<2% each): pain, swelling, heat, redness, and/or fluid build-up in or around the knee. Tell your doctor if you experience any side effects after treatment with Synvisc-One.

    View the complete prescribing information for Synvisc-One. (PDF)

    ©2014 Genzyme Corporation, a Sanofi Company. All rights reserved. Synvisc-One, SYNVISC and GENZYME are registered trademarks of Genzyme Corporation. US.SYN.14.02.038

Synvisc-One® (hylan G-F 20) is indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, e.g., acetaminophen.

Important Safety Information for Synvisc-One

Before trying Synvisc-One, tell your doctor if you have had an allergic reaction, such as swelling of the face, tongue or throat, respiratory difficulty, rash, itching or hives to SYNVISC or any hyaluronan-based products. View more