A Different Type of Osteoarthritis Treatment
Did you know that osteoarthritis knee pain is caused by more than just cartilage loss?
In knees with osteoarthritis, the joint fluid also loses its ability to absorb shock, which can result in osteoarthritis knee pain. A viscosupplement injection is a treatment that supplements your natural joint fluid to give your knee the lubrication and cushioning it needs to provide osteoarthritis knee pain relief.
How Synvisc-One Works?How do I know if Synvisc-One is right for me?
Synvisc-One is a one-injection treatment that supplements the fluid in your knee to help lubricate and cushion the joint. Synvisc-One is the #1 prescribed viscosupplement; it provides up to six months of osteoarthritis knee pain relief with just one injection.*
What is Synvisc-One made from?
Synvisc-One is for people with knee osteoarthritis who have not received enough pain relief from diet, exercise, and over-the-counter pain medication. If you've tried these options and are still feeling knee pain, ask your doctor if Synvisc-One could help.
Will the injection hurt?
The injection contains a gel-like mixture made from a substance called hyaluronan (pronounced hy-aI-u-ROE-nan) that comes from chicken combs. Hyaluronan is a natural substance found in the body and is present in very high amounts in joints. The body's own hyaluronan acts like a lubricant and a shock absorber in the joint and is needed for the joint to work properly.
What are the side effects?
The doctor will likely apply a numbing agent before a Synvisc-One injection. You may feel some pressure.
Is it covered by insurance?
The most common side effects are pain, swelling, heat, redness and/or fluid build-up around the knee. In a medical study less than 6% of patients experienced these side effects, which were generally mild and did not last long.
Synvisc-One is covered by Medicare and most insurance plans.
Watch this 2 minute video to learn about a different treatment. Synvisc-One is the #1 prescribed viscosupplement, it provides up to six months of pain relief with just one injection.
*As shown in a medical study comparing Synvisc-One to an injection of salt water.
† The views presented herein are solely those of Dr. DiNubile, Orthopaedic Surgeon. Sanofi US does not endorse Dr. DiNubile or his book, FrameWork. Dr. DiNubile is a paid advisor for Sanofi US. Be sure to consult with your own doctor before starting any exercise program or health regimen.
Synvisc-One® (hylan G-F 20) is indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, e.g., acetaminophen.Important Safety Information
Before trying Synvisc-One, tell your doctor if you have had an allergic reaction, such as swelling of the face, tongue or throat, respiratory difficulty, rash, itching or hives to SYNVISC or any hyaluronan-based products. Allergic reactions, some which can be potentially severe, have been reported during the use of Synvisc-One. Should not be used in patients with an infected knee joint, skin disease or infection around the area where the injection will be given, and should be used with caution when there is swelling of the legs due to problems with venous stasis or lymphatic drainage.
Synvisc-One is only for injection into the knee, performed by a doctor or other qualified health care professional. Synvisc-One has not been tested to show pain relief in joints other than the knee. Tell your doctor if you are allergic to products from birds – such as feathers, eggs or poultry – or if your leg is swollen or infected.
Synvisc-One has not been tested in children (≤21years old), pregnant women or women who are nursing. You should tell your doctor if you think you are pregnant or if you are nursing a child.
Talk to your doctor before resuming strenuous weight-bearing activities after treatment.
The side effects sometimes seen after Synvisc-One include (<2% each): pain, swelling, heat, redness, and/or fluid build-up in or around the knee. Tell your doctor if you experience any side effects after treatment with Synvisc One.
View the complete prescribing information for Synvisc-One. (PDF)
©2015 Genzyme Corporation, a Sanofi Company. All rights reserved. Synvisc-One, SYNVISC and GENZYME are registered trademarks of Genzyme Corporation. US.SYN.15.03.005
Synvisc-One® (hylan G-F 20) is indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, e.g., acetaminophen.
Before trying Synvisc-One, tell your doctor if you have had an allergic reaction, such as swelling of the face, tongue or throat, respiratory difficulty, rash, itching or hives to SYNVISC or any hyaluronan-based products. View more