Erectile Dysfunction and Adderall XR: Is There a Connection?

Is Adderall XR Causing My Erectile Dysfunction?

Adderall XR and Erectile Dysfunction


  1. Adderall XR is a nervous system stimulant that is commonly prescribed to treat attention deficit hyperactivity disorder (ADHD).
  2. If you take Adderall XR, you may experience changes in your sexual desire (libido). In this way, it may contribute to erectile dysfunction.
  3. If you think Adderall XR may be causing your ED, talk to your doctor before you stop taking it.

Adderall XR

Adderall XR is a medication containing dextroamphetamine and amphetamine. This medication is a nervous system stimulant that alters substances in your brain. It’s prescribed for treatment of attention deficit hyperactivity disorder (ADHD). It can also be used to treat narcolepsy, a sleep disorder. It’s designed to help keep you focused and in control of your actions. It’s prescribed for children, teens, and adults.

Adderall XR is an extended-release capsule to be taken once each morning, with or without food.

Erectile Dysfunction

Erectile dysfunction (ED) is when you can’t get an erection or can’t keep it long enough for intercourse. It almost always involves poor blood flow to the penis. There are many potential causes of ED, including underlying disease or injury. Psychological issues, stress, and anxiety can also lead to sexual dysfunction.

ED can also be a medication side effect.

Side Effects of Adderall XR

There are many potential side effects of Adderall XR. Among the more common ones are:

  • headache
  • high blood pressure, which may occur briefly after taking the drug
  • trouble sleeping
  • dry mouth
  • changes in appetite

Adderall XR may cause circulatory problems, especially in fingers and toes. It may not be safe to take Adderall XR if you have heart problems.

Benefits of Adderall XR

When you and your doctor decide to begin any medication, you should consider the risks and the benefits. Depending on each individual case, the benefit may outweigh the risks. Benefits of Adderall XR for people with ADHD include:

  • focusing on tasks
  • increased concentration
  • paying attention for a longer period of time

The Link Between Adderall XR and Erectile Dysfunction

It’s possible that Adderall XR is causing your ED. ED is usually caused by a decreased blood flow to the penis. It could also be a warning sign of another health problem or caused by various other factors like stress, nerves, and hormones.

Adderall XR is a central nervous stimulant. It affects the levels of neurotransmitters in your brain. These can influence energy levels and your mood overall. Mood can affect your ability to have an erection. Adderall XR can affect mood and cause nervousness and anxiety. These can all contribute to ED.

If you take Adderall XR, you may experience changes in your sexual desire (libido). It may be less or it may be more intense. It is possible to have increased desire even with ED.

Adderall XR can also lead to ED due to issues with circulatory problems, blood pressure, and heart rate. If you have heart disease or circulation problems, you should not take Adderall XR. 

Adderall XR and Possible Effects on Women’s Libido

As mentioned above, Adderall XR affects your energy levels, mood, and can cause nervousness and anxiety. Each of these side effects could have an effect on a woman’s sexual desire as well, either negatively or positively. This change may be an increase or a decrease in your libido. As with ED, if the changes in your libido are bothersome, be sure to discuss them with your doctor.

Managing ED While Taking Adderall XR

Since ED can be caused by any number of things, it doesn’t necessarily mean that Adderall XR is the cause. Still, Adderall XR is a powerful drug. Make sure to report all side effects to your doctor right away.

If you think Adderall XR may be causing your ED, talk to your doctor before you stop taking it. If you’ve been taking it for a long time, or are on a high dose, your doctor can help you stop taking it safely. That usually requires slowly lowering the dose and tapering off to avoid withdrawal. Your doctor may also change your prescription to a shorter acting version of this drug, which may decrease side effects.

Your doctor may also want to look into other causes for your ED, including:

  • hormone problems
  • heart disease
  • neurological disease
  • diabetes
  • liver or kidney disease
  • depression
  • other medications

If you do have an underlying medical condition, treating that could solve your ED.

You should also consider that certain behaviors could lead to or at least contribute to sexual dysfunction. These include alcohol consumption, smoking, and not getting enough exercise.

When to See Your Doctor

As with all medications, Adderall XR comes with a list of potential side effects and cautions. Sometimes, it takes a while to find the right dose of the right drug to make any side effects manageable. That’s why it’s so important to work with your doctor to find the solution that works best for you.

ED is a potential side effect of Adderall XR. Any time a side effect of a drug is bothersome, it is important to discuss it with your doctor. However, there are some serious complications and side effects of Adderall XR and related to ED that you should contact a medical professional about immediately.

Complications of Adderall XR

This medication may cause new or worsening psychiatric symptoms. Adderall XR can interact with other medications. You should not take Adderall XR if you are taking monoamine oxidase inhibitors (MAOIs) or have taken them within the previous 14 days. MAOIs are a type of antidepressant.

Some common drugs like omeprazole (Prilosec) or antacids that you buy over the counter can interact adversely with Adderall XR.

Some other drugs can increase or reduce the effects of Adderall XR. Make sure you ask your doctor or pharmacist about drug interactions between Adderall XR and your other medications.

Adderall XR is a federally controlled substance. That’s because it can be habit-forming. You should not take Adderall XR if you’ve ever had a substance abuse problem. If you stop taking it suddenly, you may enter a period of withdrawal.

Risks and Warnings

Serious side effects for ED are generally caused by the treatment or medications. However, ED can be a sign of a more serious illness or a risk factor for other health issues later such as heart disease.

You should also see your doctor immediately if you are experiencing ED and you have the following:

  • diabetes
  • heart disease
  • another health condition that might be linked to ED
  • other symptoms besides just ED
  • you have any concerns

Other Possible Serious Side Effects of Adderall XR:

  • abuse and dependence
  • heart problems
  • stroke
  • severe mood swings


If your ED is from other causes, there are treatments, medications, and some natural supplements that may be able to give you relief.

Some medications include:

  • sildenafil (Viagra)
  • tadalafil (Cialis)
  • vardenafil (Levitra, Staxyn)
  • avanafil (Stendra)

Other treatments include injections, suppositories, and testosterone replacement therapy. If medications do not work or you are not able to take them for other reasons, there are options. These options include: penis pumps, penile implants, and blood vessel surgery. These options are not as commonly used as medications.

There are also some natural supplements that have shown some promise with ED. But, it must be noted that they may have negative interactions with other medications. That includes other ED medications. Always discuss it with your doctor before taking any natural supplements or vitamins.

Some natural supplements used to treat ED include:

  • dehydroepiandrosterone (DHEA)
  • L-arginine (do not take with Viagra)
  • ginseng
  • propionyl-L-carnitine

Two common natural supplements are among those that are considered dangerous due to side effects. They are:

  • ginkgo
  • horny goat weed (epimedium)

Many men never discuss ED with their doctor. It is important to remember that ED is very common. There are many treatments that can help or even rid you of ED. If you are taking Adderall XR or any other medications and you think that may be the cause, you need to discuss this with your doctor as soon as possible. This will allow them to determine the cause of your ED and, if it is caused by your medication, it can then be adjusted to relieve ED.

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