The most common side effects that occur with diclofenac include:
itchy skin. Call your doctor if this is severe. It could be the sign of an allergic reaction.
sleepiness. See how you feel before driving or operating machinery.
If you experience any of these serious side effects, call your doctor right away. If your symptoms are potentially life-threatening, or if you think you're experiencing a medical emergency, call 9-1-1.
symptoms of allergic reaction, including itching, rash, breathing problems, or hives. If you're allergic to aspirin or other NSAIDs, you may be allergic to diclofenac.
symptoms of edema, including swelling of the feet or ankles, increased blood pressure, ringing of the ears, or increased weight
symptoms of stomach ulcer or stomach bleeding, including very dark stools or blood in your stool
bruising more easily
Diclofenac may cause drowsiness.
- Cataflam (diclofenac potassium immediate release tablets). (2011, February). Retrieved from http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020142s021s022lbl.pdf
- Diclofenac potassium- diclofenac potassium tablet, film coated. (2013, May). Retrieved from http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8e6e1aea-d1c9-f6bf-2a8c-0504437be95c
Content developed in collaboration with Susan J. Bliss, RPh, MBA
Medically reviewed by Stacey Boudreaux, PharmD and Alan Carter, PharmD on February 3, 2015