Lexapro and Weight Loss: What You Need to Know


Lexapro (escitalopram) is an antidepressant often prescribed to treat depression and anxiety disorders. Antidepressants are generally quite helpful. But as a side effect, some of these drugs may affect your weight. Let’s take a look at what’s known about Lexapro, weight, and other factors about this drug.


Lexapro and weight

Lexapro’s effect on weight

Lexapro can cause changes in weight. There are some reports that people begin to lose weight when first taking Lexapro, but this finding is not well supported by research studies.

Another study found that Lexapro didn’t reduce the obsessive-compulsive symptoms linked to binge-eating disorder, but it did reduce weight and body mass index. This may be because study participants taking Lexapro had fewer binge-eating episodes. 

More thorough research is needed on the topic of Lexapro and weight changes. But the current evidence seems to suggests that the drug may be more likely to cause weight loss than weight gain, if you have weight changes at all.

If either of these effects is a concern for you, talk to your doctor. They have the most insight on how this drug will affect you individually. They can also offer tips for managing your weight.


What it treats

What Lexapro is used to treat

Lexapro belongs to a class of antidepressants called selective serotonin reuptake inhibitors (SSRIs). These medications work by increasing the levels of serotonin in your brain. Serotonin is a key messenger chemical that helps regulate your mood.


Lexapro treats depression, a medical illness and a mood disorder that continues for longer than a few weeks. Most people with depression have deep feelings of sadness. They also lack interest in things that once gave them pleasure. Depression affects every aspect of life, including relationships, work, and appetite.

Treatment works
According to the Depression and Bipolar Support Alliance, approximately 80 percent of people with depression improve significantly with treatment.

If Lexapro helps reduce your depression, it can reverse changes in your appetite caused by the condition. In turn, you may lose or gain some weight. But this effect is more related to your condition than to side effects of the drug.


Lexapro also treats anxiety in many anxiety disorders.

Our bodies are programmed with an automatic fight-or-flight response. Our heart beats faster, our breathing becomes rapid, and more blood flows into the muscles of our arms and legs as our bodies prepare to either run or stand our ground and fight. If you have an anxiety disorder, your body goes into fight-or-flight mode more often and for longer periods of time.

There are several different anxiety disorders, including:

  • generalized anxiety disorder
  • obsessive-compulsive disorder
  • posttraumatic stress disorder
  • panic disorder
  • simple phobia
  • social anxiety disorder

Side effects

Side effects of Lexapro

FDA warning
People who are younger than 25 years should be closely monitored when taking an antidepressant. There is an increased risk of suicidal thoughts and suicide in this age group. It is more likely when they first start taking the drug, during a change in dosage, or when they stop using it.

Although it is not completely clear how Lexapro can affect your weight, other possible side effects of this drug are clear. Most people tolerate Lexapro reasonably well. Still, the following side effects are possible when you take this drug:

  • headache
  • nausea
  • dry mouth
  • fatigue
  • weakness
  • sleep disturbances
  • sexual problems
  • increased sweating
  • loss of appetite
  • constipation

Talk to your doctor


It’s not likely you’ll have weight changes because of Lexapro. More importantly, if your doctor has prescribed Lexapro, it will likely be effective in reducing your symptoms of depression or anxiety. If you’re concerned about changes to your weight while taking Lexapro, talk to your doctor. You can also ask about lifestyle changes you can make to help counter any weight changes.

Also, be sure to tell your doctor about any other changes you experience when taking Lexapro. Chances are your doctor will be able to change your dosage or have you try another drug.

Keep reading: Safe diets and healthful weight loss »

Article Resources
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  • Guerdjikova, A. I., McElroy, S. L., Kotwal, R., Welge, J. A., Nelson, E., Lake, K., … Hudson, J. I. (2008, January). High-dose escitalopram in the treatment of binge-eating disorder with obesity: A placebo-controlled monotherapy trial. Human Psychopharmacology, Clinical & Experimental, 23(1), 1–11. Retrieved from
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  • Walke, Y. S. C., & Pereira, Y. S. (2011, August). Changes in weight and body mass index with amitriptyline, fluoxetine, and escitalopram therapy. Priory Medical Journals. Retrieved from