Arrhythmia Drugs

A Guide to Drugs for Arrhythmia


An arrhythmia is a condition in which the heart beats too quickly, too slowly, or irregularly. In many cases, the arrhythmia may not be serious or require any treatment at all. However, if your doctor finds that the arrhythmia could lead to more serious heart problems, they may prescribe medication.

Several types of medication can help control or resolve an arrhythmia. The type that’s right for you depends on the kind of arrhythmia you have. Here’s what to know about drugs that treat arrhythmia.

Antiarrhythmic drugs

Antiarrhythmic drugs may be prescribed for people with tachycardia (fast heart rate) or premature or extra heartbeats. These medications work to correct the rhythm of the heart. They restore a normal heart rhythm by changing the electrical current that makes your heart beat.

Antiarrhythmic drugs come in pill form and are typically used long-term. In emergencies, they can be given intravenously. The most common medications in this class are:

Drug interactions
If you have an arrhythmia, you may be prescribed more than one medication. You should know how these drugs may interact with each other. Tell your doctor about all medications you take to make sure they’re safe to use together, and check with your doctor before taking any new medications, supplements, or vitamins.
  • amiodarone (Cordarone, Pacerone)
  • flecainide (Tambocor)
  • ibutilide (Corvert), which can only be given through IV
  • lidocaine (Xylocaine), which can only be given through IV
  • procainamide (Procan, Procanbid)
  • propafenone (Rythmol)
  • quinidine (many brand names)
  • tocainide (Tonocarid)

While these medications can help correct an arrhythmia, there is also a risk that they can cause the arrhythmia to happen again or more often. This is called a proarrhythmia. If you develop a proarrhythmia while taking an antiarrhythmic drug, call your doctor right away.

Calcium channel blockers

If you have angina (chest pain), high or low blood pressure, and an arrhythmia, your doctor may prescribe a calcium channel blocker. These drugs dilate your blood vessels. This allows more blood to flow to the heart, which helps ease chest pain and decrease blood pressure.

These drugs can also slow your heart rate. A reduced heart rate and lowered blood pressure reduce the strain on your heart and reduce your risk of an arrhythmia.

Most calcium channel blockers come in pill form, but some are also available in intravenous (IV) form. Calcium channel blockers are for long-term use.

Examples of common calcium channel blockers include:

The side effects of these medications vary. Some people have tachycardia, dizziness, constipation, and headaches. Other, more serious side effects include rash or swelling in the legs and feet.

Beta blockers

If you’ve been diagnosed with tachycardia, your doctor may prescribe a beta blocker. Beta blockers stop the action of the hormone adrenaline. This can relieve your tachycardia by slowing your heart rate. It can also lower your blood pressure and decrease the stress on your heart. Examples of beta blockers include:

Beta blockers aren’t typically prescribed for people with diabetes or asthma because they may make these conditions worse.

The side effects of beta blockers include tiredness, cold hands, and headache. Sometimes these medications affect your digestive system as well. Some people report stomach issues, constipation, or diarrhea.


An anticoagulant is a blood-thinning medication. Your doctor may prescribe an anticoagulant if your arrhythmia puts you at risk of clots or stroke caused by a clot. For some people, an abnormal heart rhythm changes how the blood flows through their system. For instance, atrial fibrillation may cause blood to pool in the heart, which may result in blood clots.

Anticoagulants don’t fix a heart rhythm problem. They only help reduce the risk of blood clots caused by certain arrhythmias.

Warfarin (Coumadin) is one of the most common anticoagulants. It’s effective, but it also makes your body less able to stop bleeding. For this reason, you should watch for any signs of internal bleeding, such as bloody stool, multiple bruises, and vomit that looks like coffee grounds.

Your doctor may prescribe aspirin instead of warfarin if they find that you have a lower risk of a blood clot. Aspirin is not as powerful of a blood thinner as warfarin is. However, it has a lower risk of causing bleeding.

Talk with your doctor

Your heart is a very important organ. To stay safe while taking your medications, try these tips:

  • Work with your doctor to understand the medications they prescribed for you.
  • Take your drugs only as directed.
  • Tell your doctor about all other medical conditions you have and medications you take.
  • Call your doctor right away if you notice anything abnormal or if you have serious side effects.

You Asked, We Answered

  • I take several heart medications. How can I manage them?
  • It’s important to keep your drugs organized so you don’t take too much or too little medication. These tips can help:

    • Use a pill dispenser to track when you should take a pill.
    • Fill all of your prescriptions at one pharmacy to make getting refills easier.
    • Keep a drug list to record all of the medications you take.

    - Healthline Medical Team

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