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Amoxicillin, Oral Tablet

Highlights for amoxicillin

  1. Amoxicillin oral tablet comes as an immediate-release (IR) tablet, an extended-release (ER) tablet, and a chewable tablet. The chewable tablets are only available as generic drugs. The IR tablets are available as both a generic and a brand-name drug. Brand name: Amoxil. The ER tablets are only available as a brand-name drug. Brand name: Moxatag.
  2. Amoxicillin also comes in the form of a capsule and a suspension. All forms are taken by mouth.
  3. Amoxicillin is an antibiotic. It’s used to treat infections caused by certain types of bacteria.
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Important warnings

Important warnings

  • Finishing therapy: It’s important to finish the entire course of treatment as prescribed by your doctor. Do not stop taking this drug or skip doses if you start to feel better. This could cause your infection to last longer. You could also develop a resistance to the medication. This means that if you get a bacterial infection in the future, you may not be able to treat it with amoxicillin.
  • Diarrhea: Amoxicillin may cause diarrhea. Call your doctor if you have bloody or watery diarrhea, with or without stomach cramps and fever.
  • Serious allergic reaction: This drug can cause a serious allergic reaction. This reaction can be fatal (cause death). If you’re allergic to other antibiotics, such as penicillins or cephalosporins, your risk for an allergic reaction may be higher. Call your doctor right away if you have trouble breathing or swelling of your throat or tongue while you’re taking this drug.

About

What is amoxicillin?

Amoxicillin oral tablet is a prescription drug that comes in the form of an immediate-release (IR) tablet, an extended-release (ER) tablet, and a chewable tablet. The chewable tablets are only available as generic drugs. The IR tablets are available as both a generic drug and the brand-name drug Amoxil. The ER tablets are only available as the brand-name drug Moxatag.

Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand-name versions.

Amoxicillin also comes as a capsule and a suspension. All forms are taken by mouth.

Why it's used

Amoxicillin is an antibiotic. It’s used to treat infections caused by a certain type of bacteria.

Amoxicillin may be used as part of a combination therapy. This means you may need to take it with other medications.

How it works

Amoxicillin belongs to a class of drugs called penicillins. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Amoxicillin works by killing bacteria and stopping its growth in your body.

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Side effects

Amoxicillin side effects

Amoxicillin oral tablet does not cause drowsiness, but it can cause other side effects.

More common side effects

The more common side effects of amoxicillin oral tablet can include:

  • nausea
  • vomiting
  • diarrhea
  • rash

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Serious side effects

Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

  • Hypersensitivity reactions. Symptoms can include:
    • flu-like symptoms, such as fever, body aches, or sore throat
    • a painful red or purple rash that spreads
    • blisters that could cause the skin to break down and cause open sores
  • Liver damage (rare). Symptoms can include:
    • increased liver enzymes shown on a blood test
    • pain in the abdomen (stomach area)
    • yellowing of the skin and whites of the eyes
    • tiredness

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.

Interactions

Amoxicillin may interact with other medications

Amoxicillin oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Examples of drugs that can cause interactions with amoxicillin are listed below.

Drugs that increase the risk of side effects from amoxicillin

Taking amoxicillin with certain medications raises your risk of side effects from amoxicillin. This is because the amount of amoxicillin in your body may be increased. Examples of these drugs include:

  • Probenacid
    • If you use these drugs together, your doctor will likely keep your dosage of amoxicillin the same.
  • Allopurinol
    • If you use these drugs together, you may develop rash.

Interactions that increase the risk of side effects from other drugs

Taking amoxicillin with certain medications raises your risk of side effects from these medications. This is because amoxicillin increases the amount of these drugs in your body. Examples of these drugs include:

  • Drugs to treat blood clots
    • If you use these drugs together with amoxicillin, you have higher risk of bleeding.

Interactions that can make your drugs less effective

When amoxicillin is less effective: When amoxicillin is used with certain drugs, it may not work as well. This is because the amount of amoxicillin in your body may be decreased. Examples of these drugs include:

  • Chloramphenicol
    • If you use these drugs together, your doctor will likely keep your dosage of amoxicillin the same.
  • Macrolides, such as erithromycin, clarithromycin, or azithromycin
    • If you use these drugs together, your doctor will likely keep your dosage of amoxicillin the same.
  • Sulfonamides, such as sulfamethoxazole
    • If you use these drugs together, your doctor will likely keep your dosage of amoxicillin the same.
  • Tetracyclines, such as tetracycline or doxycycline
    • If you use these drugs together, your doctor will likely keep your dosage of amoxicillin the same.

When other drugs are less effective: When certain drugs are used with amoxicillin, they may not work as well. This is because the amount of these drugs in your body may be decreased. Examples of these drugs include:

  • Oral contraceptives (birth control)
    • If you need to take amoxicillin, your doctor may prescribe a different form of birth control for you.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

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Other warnings

Amoxicillin warnings

This drug comes with several warnings.

Allergies

Amoxicillin can cause a severe allergic reaction. Symptoms can include:

  • trouble breathing
  • swelling of your throat or tongue

If you have an allergic reaction, call your doctor or local poison control center right away. If your symptoms are severe, call 911 or go to the nearest emergency room. Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).

Warnings for people with certain health conditions

For people with mononucleosis (mono or kissing disease): Amoxicillin raises your risk of developing a severe rash.

For people with diabetes: Amoxicillin may cause you to have a false positive reaction when testing for glucose (sugar) in the urine. Talk with your doctor about how to manage your blood sugar while taking amoxicillin.

For people with kidney disease: If you have severe kidney disease, your kidneys may not clear this drug from your body quickly. As a result, levels of amoxicillin may build up in your body. To help prevent this, your doctor may give you a lower dose of this drug.

Warnings for other groups

For pregnant women: Amoxicillin is a category B pregnancy drug. That means two things:

  1. Research in animals has not shown a risk to the fetus when the mother takes the drug.
  2. There aren’t enough studies done in humans to show if the drug poses a risk to the fetus.

Talk to your doctor if you’re pregnant or planning to become pregnant. Animal studies do not always predict the way humans would respond. Therefore, this drug should only be used in pregnancy if clearly needed.

Call your doctor right away if you become pregnant while taking this drug.

For women who are breastfeeding: Amoxicillin may pass into breast milk and may cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication.

For seniors: The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects.

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Dosage

How to take amoxicillin

This dosage information is for amoxicillin oral tablet. All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:

  • your age
  • the condition being treated
  • how severe your condition is
  • other medical conditions you have
  • how you react to the first dose

Forms and strengths

Generic: Amoxicillin

  • Form: oral tablet
  • Strengths: 500 mg, 875 mg
  • Form: oral chewable tablet
  • Strengths: 125 mg, 200 mg, 250 mg, 400 mg

Brand: Moxatag

  • Form: oral extended-release tablet
  • Strengths: 775 mg

Brand: Amoxil

  • Form: oral tablet
  • Strengths: 500 mg, 875 mg

Dosage for infections of the ears, nose, and throat

IMMEDIATE-RELEASE TABLET AND CHEWABLE TABLET

Adult dosage (ages 18–64 years)

Typical dosage is 500 mg every 12 hours, or 250 mg every 8 hours.

Child dosage (ages 3 months–17 years)

Typical dosage is 25 mg/kg/day in divided doses every 12 hours, or 20 mg/kg/day in divided doses every 8 hours.

Child dosage (ages 0–2 months)

Maximum dosage is 30 mg/kg/day. Your child’s doctor can tell you more about dosage.

EXTENDED-RELEASE TABLET

Adult dosage (ages 18–64 years)

  • Typical dosage is 775 mg once per day for 10 days.
  • Take within 1 hour of finishing a meal.

Child dosage (ages 12–17 years)

  • Typical dosage is 775 mg once per day for 10 days.
  • Take within 1 hour of finishing a meal.

Child dosage (ages 0–11 years)

It has not been confirmed that amoxicillin extended-release tablets are safe and effective for use in people younger than 12 years of age.

Senior dosage (ages 65 years and older)

The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects.

Your doctor may start you on a lowered dose or a different dosing schedule. This can help keep levels of this drug from building up too much in your body.

Special considerations

  • For children’s dosage: The children’s dosage listed here is meant for children who weigh less than 88 pounds (40 kg). Children who weigh more than 88 pounds should be dosed according to the adult recommendations.

Dosage for urinary tract infections

Adult dosage (ages 18–64 years)

Typical dosage is 500 mg every 12 hours, or 250 mg every 8 hours.

Child dosage (ages 3 months–17 years)

Typical dosage is 25 mg/kg/day in divided doses every 12 hours, or 20 mg/kg/day in divided doses every 8 hours.

Child dosage (ages 0–2 months)

Maximum dosage is 30 mg/kg/day. Your child’s doctor can tell you more about dosage.

Senior dosage (ages 65 years and older)

The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects.

Your doctor may start you on a lowered dose or a different dosing schedule. This can help keep levels of this drug from building up too much in your body.

Special considerations

  • For children’s dosage: The children’s dosage listed here is meant for children who weigh less than 88 pounds (40 kg). Children who weigh more than 88 pounds should be dosed according to the adult recommendations.

Dosage for skin infections

Adult dosage (ages 18–64 years)

Typical dosage is 500 mg every 12 hours, or 250 mg every 8 hours.

Child dosage (ages 3 months–17 years)

Typical dosage is 25 mg/kg/day in divided doses every 12 hours, or 20 mg/kg/day in divided doses every 8 hours.

Child dosage (ages 0–2 months)

Maximum dosage is 30 mg/kg/day. Your child’s doctor can tell you more about dosage.

Senior dosage (ages 65 years and older)

The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects.

Your doctor may start you on a lowered dose or a different dosing schedule. This can help keep levels of this drug from building up too much in your body.

Special considerations

  • For children’s dosage: The children’s dosage listed here is meant for children who weigh less than 88 pounds (40 kg). Children who weigh more than 88 pounds should be dosed according to the adult recommendations.

Dosage for lower respiratory tract infections

Adult dosage (ages 18–64 years)

Typical dosage is 875 mg every 12 hours, or 500 mg every 8 hours.

Child dosage (ages 3 months–17 years)

Typical dosage is 45 mg/kg/day in divided doses every 12 hours, or 40 mg/kg/day in divided doses every 8 hours.

Child dosage (ages 0–2 months)

Maximum dosage is 30 mg/kg/day. Your child’s doctor can tell you more about dosage.

Senior dosage (ages 65 years and older)

The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects.

Your doctor may start you on a lowered dose or a different dosing schedule. This can help keep levels of this drug from building up too much in your body.

Special considerations

  • For children’s dosage: The children’s dosage listed here is meant for children who weigh less than 88 pounds (40 kg). Children who weigh more than 88 pounds should be dosed according to the adult recommendations.

Dosage for gonorrhea

Adult dosage (ages 18–64 years)

Typical dosage is 3 g as a single dose.

Child dosage (ages 24 months–17 years)

Typical dosage is 50 mg/kg amoxicillin combined with 25 mg/kg probenecid as a single dose.

Child dosage (ages 0–23 months)

This medication should not be used children younger than 2 years for treatment of gonorrhea.

Senior dosage (ages 65 years and older)

The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects.

Your doctor may start you on a lowered dose or a different dosing schedule. This can help keep levels of this drug from building up too much in your body.

Special considerations

  • For children’s dosage: The children’s dosage listed here is meant for children who weigh less than 88 pounds (40 kg). Children who weigh more than 88 pounds should be dosed according to the adult recommendations.

Dosage for stomach and intestinal ulcers

Adult dosage (ages 18–64 years)

  • Typical dosage for triple therapy: 1 g amoxicillin with 500 mg clarithromycin and 30 mg of lansoprazole, all given twice per day for 14 days.
  • Typical dosage for dual therapy: 1 g amoxicillin and 30 mg of lansoprazole, given three times per day for 14 days.

Child dosage (ages 0–17 years)

This drug has not been studied in children to treat stomach and intestinal ulcers.

Senior dosage (ages 65 years and older)

The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects.

Your doctor may start you on a lowered dose or a different dosing schedule. This can help keep levels of this drug from building up too much in your body.

Special considerations

  • For children’s dosage: The children’s dosage listed here is meant for children who weigh less than 88 pounds (40 kg). Children who weigh more than 88 pounds should be dosed according to the adult recommendations.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always to speak with your doctor or pharmacist about dosages that are right for you.

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Take as directed

Take as directed

Amoxicillin oral tablet is used for short-term treatment. It comes with serious risks if you don’t take it as prescribed.

If you stop taking the drug suddenly or don’t take it at all: Your bacterial infection may not heal, or may get worse.

If you miss doses or don’t take the drug on schedule: Your medication may not work as well or may stop working completely. For this drug to work well, a certain amount needs to be in your body at all times.

It’s important to finish the entire course of treatment as prescribed by your doctor. Do not stop taking the drug or skip doses if you start to feel better. This could cause your infection to last longer. You could also develop a resistance to the medication. This means if you get a bacterial infection in the future, you may not be able to treat it with amoxicillin.

If you take too much: You could have dangerous levels of the drug in your body. Symptoms of an overdose of this drug can include:

  • stomach upset
  • diarrhea

If you think you’ve taken too much of this drug, call your doctor or local poison control center. If your symptoms are severe, call 911 or go to the nearest emergency room right away.

What to do if you miss a dose: Take your dose as soon as you remember. But if you remember just a few hours before your next scheduled dose, take only one dose. Never try to catch up by taking two doses at once. This could result in dangerous side effects.

How to tell if the drug is working: The symptoms of your infection should improve.

Important considerations

Important considerations for taking amoxicillin

Keep these considerations in mind if your doctor prescribes amoxicillin oral tablet for you.

General

  • Take this drug at the time(s) recommended by your doctor.
  • You can take the amoxicillin capsule, tablet, chewable tablet, or suspension with or without food.
  • You should take amoxicillin extended-release tablets within 1 hour of finishing a meal.
  • Don’t crush, cut, or chew the extended-release tablets. You can crush, cut, or chew the regular or chewable tablets.

Storage

  • Store amoxicillin at room temperature between 59°F and 86°F (15°C and 30°C).
  • Keep this drug away from light.
  • Don’t store this medication in moist or damp areas, such as bathrooms.

Refills

A prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.

Travel

When traveling with your medication:

  • Always carry your medication with you. When flying, never put it into a checked bag. Keep it in your carry-on bag.
  • Don’t worry about airport x-ray machines. They can’t hurt your medication.
  • You may need to show airport staff the pharmacy label for your medication. Always carry the original prescription-labeled box with you.
  • Don’t put this medication in your car’s glove compartment or leave it in the car. Be sure to avoid doing this when the weather is very hot or very cold.

Clinical monitoring

You and your doctor should monitor certain health issues. This can help make sure you stay safe while you take this drug. These issues include your:

  • Kidney function. Blood tests can check how well your kidneys are working. If your kidneys aren’t working well, your doctor may decide to lower your dosage of this drug.
  • Liver function. Blood tests can check how well your liver is working. If your liver isn’t working well, your doctor may lower your dosage of this drug.

The cost of these blood tests will depend on your insurance coverage.

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Alternatives

Are there any alternatives?

There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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