CCTYPE html> content="NOODP" itemtype="s:fb="" class="no-js hl-reset" lang="en"> had" /> script type="text/javascript">s if (roadblockId == null) var roadblockId = 0; // NAVIGATOR: since -1 is DB default, a negative condition against 0 will pass and NOT roadblock any ads slink href="/resources/healthline/css/site.less?v=v1.20140722121124" type="text/css" rel="stylesheet"/> llnhhref"/>esheet"/> 4link href="/resources/healthline/css/rwd/article.less?v=v1.20140722121124" media="all" type="text/css" rel="stylesheet"/>nn n n l sscript src="//">/script> safrmPagType: "regularArticle", stHL_ga_customVars); ga_url_msId_fragment = ''; // make sureokeep microsite n URL _gaq.push(['hl_rackPageview', window.location.pathname + + HL_ga_u_sId_fragment + window.locati _gaq.push(HL_ga_ckTimeOnPageWrapper); _gaq.push(HL_ga_track90percentScrollWrapper); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript';cation.protocol ? 'https://' : 'http/') + '';sprentNode.insertBefore(ga, s); })(); }); // requireoule> /div> div class="hl-main-content"> div class="hl headerbdiv class="hl headerblock"> lobal_nav" class="c"> div class="top-menu-sticky">div class="top-menu-sticky"> lass="box-globalnav c">c"> !-- box-sticky --> /div> v> /div> div>!-- TC header -->>iv id="hl" class="hl"> div class="bodycontainer bclayerie7">7"> v class="innerbodybox"> div class="container c"> iv class="grid648"> v itemscope itemtype="" class="container-article"> div itemprop="headline" class="article-header c"> llergies: Are They in Your Genes? /h1> itemprop="description" class="subhead">Allergies may be linked to genetics. Read more about recent research showing that genetics may be key in treating allergies. /p> /div> class="box-byblock c"> class="byline"> Written by an itemprop="author">Michael Kerrn> | Published on meta itemprop="datePublished" content="2012-05-04">May 4, 2012/>Medically Reviewed by George Krucik, MD> />v> div class="hl-widget-sharebar c">/div> class="dotted-line">> div class="text-resize">> d="text1" class="text1 s /div> /div> class="ads-box-right-lb">> /div>>div class="hl"> class="persist-area"> class="persist-header"> class="box-outer-sticky"> div class="box-sticky layerie7"> div class="box-inner-sticky layerie7"> lass="breadcrumb"> li itemscope itemtype=""> Allergy and the Center for Allergy and Environment (ZAUM) ofand Allergy anhe Center for Allergy and Environment (ZAUM) ofd Environment (ZAUM) ofZAUM) ofthe Technical University of Munich, discovered a "major gene for allergicunich, discovered a "major gene for allergicd a "major gene for alcdiseases." The gene, FCER1A, encodes the alpha chain "of high" The gene, FCER1A, encodes the alpha chain "of high affinity IgE recept according to the study. thdy.

/p> p>"Most people with allergies are atopic," explained lead esearcher Stephan Weidinger, " they have a genetic tendency toave a genetic tendency to a genetic tendency to todevelop allergies. Tct the genetors we examined the genomes ofd the genomes ofs ofmore than 10,000 adults and children from the whole of Germany." 10,000 adults and children from the whole of Germany." hildren from the whole of Germany." le of Germany." Germany." /p> p> hese findings are already helping to guide research into the elopment of new , which could help provide relief for millions of llergy sufferers worldwide./p> h2>Immunology/h2>/h2> p>Currently, physicians can treat certain allergies by giving tients repeated low-dose shots of an allergen, which leads to a tolerance ofan allergen, which leads to a tolerance ofa tolerance ofthose ances. The procedure, known as de-sensitization, doesn't work forrocedure, kns de-sensitization, doesn't work fordoesn't work for everyone, however. /p> p>For instance, those with severe food alies may be put at risk of deadly anaphylactic shock by the treatment itself. eatment itself. ent itself.

/p> p>New research, based on the earlier gene studies, may help. Investigators working with genetically engineered proteins have found that theylly engineered proteins have found that theyund that they can interfere with the types of allergic reactions that cause hay fever, asthma,re with the t of allergic react that cause hay fever, asthma,cause hay fever, asthma,ver, asthma,a,ertain food allergies—at least in mice. /p> >Researchers are hopeful that they'll work in human beings as well.hat they'll work in human beings as in human beings as well.ngs as well. According to Andrew Saxon who is leading the studies at the University ofleading the studies at the University ofhe University offlifornia, Los Angeles, the new treatment may eventually help to "defuse the new treatment may eventually help to "defusement may eventually help to "defuselly help to "defuseo "defuse the allergy bomb" and allow even the most sensitive patients to receivellow ethe most sensitiveen receive the shots.p; div class="box-pagination c">div class="box-pagination c"> cript> <