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Grand Rounds 4.27 at Monash Medical Student
Many thanks to Jeffrey Leow at Monash Medical Student for the hard work in putting together a great collection of Grand Rounds offerings. Thanks also for including a link to my recent post that reviewed Chromosomal Mosaicism Detected at the Time ...
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Groundrules for Comments and Communication
As some of our regular readers already know, about 6 months ago I took on the role of interim Chair in our Department of OB/GYN. The added responsibilities have drastically cut into the time and energy I have had to devote to this site, although ...
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Amniotic Fluid - 3 - Oligohydramnios: Causes of Too Little Amniotic Fluid
Having discussed where amniotic fluid comes from and how we assess amniotic fluid volume, let’s address the most common amniotic fluid abnormality – too little fluid or oligohydramnios. There are 3 primary reasons why there is too little amniotic...
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Recurrent Early Pregnancy Loss - 7 - Immunologic and Hematologic Causes
Our blood clotting system helps prevent us from bleeding and also may potentiate an immune response since it is ‘activated’ by tissue damage. Blood clotting (coagulation or thrombosis) and the breaking down of blood clots (fibrinolysis or thrombo...
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Grand Rounds 3.52 - Thanks Kerri!
Many thanks and congratulations to Kerri at Six Until Me for this week's Grand Rounds 3.52 and for including my recent post on a "A Complication of Methotrexate Use for Ectopic Pregnancy." My compliments on the nourishing selection of posts for bo...
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Hypertensive Disorders of Pregnancy - 8 (9 and 10!)
I started this article 3-4 days ago and was about to post it to the site last night and realized it looked more like a scientific review article for the New England Journal of Medicine than anything most of you would care to read. So, I have pared...
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Abnormal Sperm Morphology and Recurrent Pregnancy Loss?
The following comment was recently received with the request to comment upon the possible association of "poor sperm quality" and recurrent pregnancy loss...Posted by Concerned_in_Canada to Fruit of the Womb at Thu Jan 31, 11:59:00 AM 2008 "Early ...
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Plasminogen Activator Inhibitor-1 (PAI-1): Role in Adverse Pregnancy Outcome? - 2 - Late Pregnancy Complications
In our last post, we discussed the role of plasminogen activator inhibitor-1 (PAI-1) in helping to maintain the balance between the clotting and fibrinolytic (clot-dissolving) sides of the coagulation system. The primary function of PAI-1 is to i...
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Cervical Dysplasia and Cancer in Pregnancy - 4
Since our last post, a reader asked the simple question, “if the patient has an abnormal Pap smear and it is not cancer, then what is it?” Although my specialty is Maternal-Fetal Medicine, and I have no delusions (or desire) to be a cancer special...
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Hypertensive Disorders in Pregnancy - 4
In our last post, we mentioned that preeclampsia is often the end-stage clinical manifestation of irreversible pathologic changes that take place early in pregnancy. Indeed, there is good evidence that abnormal early placental development plays a ...
