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Fruit of the Womb
Fruit of the Womb
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  • Understanding Interpretation of First Trimester Screening Results

    Based on the very large number of comments and questions I continue to receive related to the interpretation of the results of ‘combined first trimester screening for aneuploidy’, it is clear that there is a lot of confusion among both patients an...

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  • Folate Receptor Antibodies and Congenital Birth Defects

    We have such great readers! The comment and questions below were shared with us by a physician who had a twin pregnancy in which both of her babies were lost early in third trimester with different major congenital birth defects - one involving t...

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  • November 14, 2006: National Prematurity Awareness Day

    Today has been designated National Prematurity Awareness Day. I know I have devoted several posts to preterm birth (PTB), and actually have several more that will eventually be committed to this blog, but in recognizing today’s significance, it i...

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  • Composite Results are the Strength of First Trimester Screening for Aneuploidy

    The reader below faces what appears to be a growing dilemma for patients (and their providers) in the laboratory reporting of results from first trimester screening for aneuploidy. The data that supports this screening modality has always emphas...

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  • X-Linked Hydrocephalus - 3 - The Role of L1CAM Mutations

    The CRASH spectrum of overlapping syndromes that are characterized by variable expression of Corpus callosum hypoplasia, Retardation, Adducted thumbs, Spastic paraplegia, and Hydrocephalus, are all the result of a variety of mutations in the cell ...

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  • ACOG Annual Meeting - San Diego - "President's Program" continued...

    …The next speaker who presented at the “Presidents Program” should have run for President herself, and I don’t mean of ACOG, Dr. Joycelyn Elders. I have heard her speak before, but this was one of her finest moments. She started with the accurate ...

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  • Plasminogen Activator Inhibitor-1 (PAI-1): Role in Adverse Pregnancy Outcome? - 3 - Association with Recurrent Pregnancy Loss

    In our last post, we reviewed several studies that would lend support to the hypothesis that women with elevated levels of plasminogen activator inhibitor-1 (PAI-1), and a genetic predisposition for the same, are at increased risk for adverse preg...

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  • Diabetes in Pregnancy - 2 - Glucose Metabolism and Insulin Action

    To continue the discussion of diabetes in pregnancy, let’s first start with a very simplified review of glucose metabolism and the role of insulin so that we understand what the furor is all about….Glucose is one of the primary substrates for the ...

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  • Indications for Doppler Flow Velocimetry During Pregnancy

    Recently, I received a phone call from our billing office reporting that an insurance company had declined to reimburse us for a claim that included charges for Doppler flow velocimetry for the indication of intrauterine growth restriction (IUGR)....

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  • Recurrent Early Pregnancy Loss: To Treat or Not to Treat...

    The readers who sent in the comments below related to recurrent early pregnancy loss (RPL) have what we could consider to be 'borderline' indications for 'treatment' and several questions related to their therapy. But, the fact remains, they have ...

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About the Author

Dr. Trofatter is an expert on maternal-fetal medicine.

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