Fruit of the Womb
Fruit of the Womb
Latest Entries
  • Breast Cancer and Pregnancy: Miscellaneous Concerns

    In my introductory comments “Breast Cancer During Pregnancy - Overview” there were several important questions for which I have not yet offered answers. Each of these could be a blog unto themselves, but to keep things moving along, let me addres...

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  • Understanding 'Rh-disease'

    When antibodies from an Rh-sensitized woman cross the placenta and enter the circulation of an Rh-positive baby, they attach to the Rh-antigens on the fetal red blood cells (RBCs). Once that occurs, the fetal immune system is fooled into believin...

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  • Polyploidy as a Cause of Early Pregnancy Loss

    Probably one of the most popular series I have written over the past few years is the one on recurrent early pregnancy loss. There is not a week that goes by that I still don’t get inquiries related to that subject, most accompanied by the pain, ...

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  • Case of Elevated Inhibin with a Midtrimester Maternal Serum Screen

    I have spent most of my free time this week, the little I seem to have anymore, catching up with all of the readers' comments that accumulated while I took my vacation. One thing that seems to be a constant in medicine is that you can turn off yo...

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  • "It was the best of times, it was the worst of times..."

    Yesterday, shortly after rounds with our residents, I was called urgently to the postpartum floor because a patient of ours was “coding” (cardiopulmonary arrest). She was a 31 year old woman who had just delivered her sixth child the day before....

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  • Grand Rounds 4.8 at Dr Anonymous!

    Thanks to Dr. Anonymous for including my last minute submission regarding the role of endometriosis in recurrent early pregnancy loss (RPL)in this week's Grand Rounds 4.8. Many women associate infertility with endometriosis, but are not aware of ...

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  • Recurrent Early Pregnancy Loss - 3 - Chromosomal Causes

    Although 50% or more of sporadic pregnancy losses in first trimester are the result of chromosomal abnormalities, these probably account for less than 5% of recurrent early pregnancy losses. There is also usually a difference in the type of chrom...

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  • Readers' Questions Regarding Rh-immune Globulin

    Like GBS (see our last post), another common source of questions and confusion in uncomplicated pregnancies is the significance of being an Rh-negative woman. It is another one of those things we screen for routinely, and when found, add to our 'p...

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  • Amniotic Fluid - 5 - Evaluation and Management of Oligohydramnios

    Just as the fetal outcome depends on the degree, underlying cause, timing during development and longevity of decreased amniotic fluid, to some extent, so do the management options. When the baby has complete absence of both kidneys (bilateral re...

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  • Methotrexate - Easy to Use, Easy to Abuse

    I received the two comments below from readers and use this opportunity of their tragic experiences to revisit a concern that I raised about two years ago regarding methotrexate therapy for the presumptive diagnosis of ectopic pregnancy….Melissa O...

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About the Author

Dr. Trofatter is an expert on maternal-fetal medicine.

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