Fruit of the Womb
Fruit of the Womb
Latest Entries
  • Rh-isoimmunization

    In our last post we discussed what it means to be 'Rh-negative' in response to a patient’s concern that she is. We also mentioned that complications related to being Rh-negative have been greatly reduced over the past 40 years by the prophylactic...

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  • Chromosomal Abnormalities and Multiple Gestations - 1

    In our practice, we see many cases of multiple gestations (mostly twins and not more, thank goodness) that come about as the result of the success of our colleagues in Reproductive Endocrinology and Infertility (REI). In general, these patients t...

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  • Understanding Interpretation of First Trimester Screening Results

    Based on the very large number of comments and questions I continue to receive related to the interpretation of the results of ‘combined first trimester screening for aneuploidy’, it is clear that there is a lot of confusion among both patients an...

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  • Maternal Serum Screening in Midtrimester

    Prenatal maternal serum screening in midtrimester (AFP, estriol, hCG, and inhibin-A) is without doubt the most misunderstood test routinely offered to women during pregnancy. Misconceptions and uncertainty abound on the parts of both patients and...

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  • X-Linked Hydrocephalus - 1 - Introduction

    Within the past year, we had the pleasure of seeing a young woman who was referred to us in early pregnancy with a strong family history of “X-linked hydrocephalus.” Indeed, she was known to be a carrier of a mutation in the cell adhesion molecul...

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  • Thanks to Dr. Bongi for a New Year's Grand Rounds

    Many thanks to Dr. Bongi at Other Things Amanzi for a most extraordinary and colorful Grand Rounds. All I can say is what a great way to start the new Year! Between the photographs of Africa and the selection of submissions, this is one Grand Rou...

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  • Plasminogen Activator Inhibitor 1 (PAI 1) and Recurrent Pregnancy Loss

    Back in June, a reader I.R. left a comment on my post "Recurrent Early Pregnancy Loss - 7 - Immunologic a...". Her specific question related to the possible role of plasminogen activator inhibitor 1 (PAI 1) activity and polymorphisms in recurrent...

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  • Readers' Concerns Regarding Rh-immune Globulin and ABO-Incompatibilty

    Anonymous said...Great information! I just miscarried and I want to know why. I am 0- and received a Rhogam shot at 28 weeks with my 1st child. I did not receive a shot after delivery--I checked my records. Did this (not receiving a shot) contribu...

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  • Cytomegalovirus (CMV) Reprise

    There is not a week that goes by in my practice that I do not have to address questions regarding cytomegalovirus (CMV) infections and pregnancy. Since we have also been discussing recurrent pregnancy loss in various contexts over the past year, ...

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  • Grand Rounds 4.36 at Parallel Universes!

    Many thanks to Parallel Universes for this week's rendition of Grand Rounds 4.36 and for including a link to my recent post on the Evaluation and Management of Polyhydramnios. The evaluation of amniotic fluid is an important part of every pregnanc...

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About the Author

Dr. Trofatter is an expert on maternal-fetal medicine.

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