Fruit of the Womb
Fruit of the Womb
Latest Entries
  • X-Linked Hydrocephalus - 3 - The Role of L1CAM Mutations

    The CRASH spectrum of overlapping syndromes that are characterized by variable expression of Corpus callosum hypoplasia, Retardation, Adducted thumbs, Spastic paraplegia, and Hydrocephalus, are all the result of a variety of mutations in the cell ...

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  • ACOG Annual Meeting - San Diego - "President's Program" continued...

    …The next speaker who presented at the “Presidents Program” should have run for President herself, and I don’t mean of ACOG, Dr. Joycelyn Elders. I have heard her speak before, but this was one of her finest moments. She started with the accurate ...

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  • Plasminogen Activator Inhibitor-1 (PAI-1): Role in Adverse Pregnancy Outcome? - 3 - Association with Recurrent Pregnancy Loss

    In our last post, we reviewed several studies that would lend support to the hypothesis that women with elevated levels of plasminogen activator inhibitor-1 (PAI-1), and a genetic predisposition for the same, are at increased risk for adverse preg...

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  • Diabetes in Pregnancy - 2 - Glucose Metabolism and Insulin Action

    To continue the discussion of diabetes in pregnancy, let’s first start with a very simplified review of glucose metabolism and the role of insulin so that we understand what the furor is all about….Glucose is one of the primary substrates for the ...

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  • Cervical Incompetence and Cerclage - 6 - Evaluation and Decisions in Midtrimester

    In the last post, we discussed the approach I have chosen to take regarding cervical incompetence and cerclage under fairly straightforward circumstances. Let’s up the ante in today’s post since I care for far more women under more urgent conditi...

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  • Recurrent Early Pregnancy Loss - 10 - Empiric Treatment

    Most patients who have recurrent early pregnancy loss are desperate to try “anything and everything” to achieve a successful pregnancy. Because of this plea, I have adopted (and often combine) both ‘empiric’ and ‘specific’ approaches to therapy ov...

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  • Call to Action: Help Raise the South Carolina Cigarette Tax

    Despite the fact I trained at an institution (and am quite grateful for the opportunity that was afforded to me) that was built on tobacco money, and I do, admittedly, enjoy the occasional fine cigar (only in the presence of consenting adults), th...

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  • The "Flu" and Pregnancy: Get Smart, Get Vaccinated NOW

    Well, the flu season is underway, and every pregnant woman wants to know, “Should I get the flu shot?” The simple answer is “YES (with few exceptions),” no matter how early or far along you are in your pregnancy, and the optimal time to receive t...

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  • Recurrent Early Pregnancy Loss - 5 - Introduction to Immunologic Causes

    The last two major categories I would like to discuss related to recurrent early pregnancy loss are immunologic and hematological (thrombophilias) abnormalities. These may well be the most common causes, but they are also by far the least well un...

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  • Blogging - Reflection of Eight Months Online at Healthline

    This week’s Grand Rounds 3.35 is going to be hosted by impactEDnurse.com. The challenge to the submitters was to “take a journey back through the narrative of your posts and pick out a story that you consider to be one of your best. Maybe it is a ...

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About the Author

Dr. Trofatter is an expert on maternal-fetal medicine.

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