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Recurrent Early Pregnancy Loss - 5 - Introduction to Immunologic Causes
The last two major categories I would like to discuss related to recurrent early pregnancy loss are immunologic and hematological (thrombophilias) abnormalities. These may well be the most common causes, but they are also by far the least well un...
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Blogging - Reflection of Eight Months Online at Healthline
This week’s Grand Rounds 3.35 is going to be hosted by impactEDnurse.com. The challenge to the submitters was to “take a journey back through the narrative of your posts and pick out a story that you consider to be one of your best. Maybe it is a ...
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Rh-isoimmunization
In our last post we discussed what it means to be 'Rh-negative' in response to a patient’s concern that she is. We also mentioned that complications related to being Rh-negative have been greatly reduced over the past 40 years by the prophylactic...
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Chromosomal Abnormalities and Multiple Gestations - 1
In our practice, we see many cases of multiple gestations (mostly twins and not more, thank goodness) that come about as the result of the success of our colleagues in Reproductive Endocrinology and Infertility (REI). In general, these patients t...
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Understanding Interpretation of First Trimester Screening Results
Based on the very large number of comments and questions I continue to receive related to the interpretation of the results of ‘combined first trimester screening for aneuploidy’, it is clear that there is a lot of confusion among both patients an...
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Folate Receptor Antibodies and Congenital Birth Defects
We have such great readers! The comment and questions below were shared with us by a physician who had a twin pregnancy in which both of her babies were lost early in third trimester with different major congenital birth defects - one involving t...
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November 14, 2006: National Prematurity Awareness Day
Today has been designated National Prematurity Awareness Day. I know I have devoted several posts to preterm birth (PTB), and actually have several more that will eventually be committed to this blog, but in recognizing today’s significance, it i...
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Composite Results are the Strength of First Trimester Screening for Aneuploidy
The reader below faces what appears to be a growing dilemma for patients (and their providers) in the laboratory reporting of results from first trimester screening for aneuploidy. The data that supports this screening modality has always emphas...
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X-Linked Hydrocephalus - 3 - The Role of L1CAM Mutations
The CRASH spectrum of overlapping syndromes that are characterized by variable expression of Corpus callosum hypoplasia, Retardation, Adducted thumbs, Spastic paraplegia, and Hydrocephalus, are all the result of a variety of mutations in the cell ...
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ACOG Annual Meeting - San Diego - "President's Program" continued...
…The next speaker who presented at the “Presidents Program” should have run for President herself, and I don’t mean of ACOG, Dr. Joycelyn Elders. I have heard her speak before, but this was one of her finest moments. She started with the accurate ...
