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Request to My Readers...
I have been writing posts for “Fruit of the Womb” for almost 20 months now. It continues to be a source of great fun and greater satisfaction. It has been an opportunity to refresh, review, explore, and relate my understanding and experiences re...
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Plasminogen Activator Inhibitor-1 (PAI-1): Role in Adverse Pregnancy Outcome? - 5 - Implantation and Placentation
Things have been so busy at work the last few weeks that it has been hard to find the time to write here, but I would like to finish up the series we started on plasminogen activator inhibitor-1 (PAI-1) and role in pregnancy outcome and recurrent ...
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Letter to My Readers
Dear Readers,A week or so back I received the comment below buried under one of my posts. It troubled me a lot, but it came at a good time, because it made me focus on some of the concerns I have had regarding my role on this site and your expec...
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Fetal Nasal Bone Assessment in First Trimester Screening for Aneuploidy
The reader below underwent combined first trimester screening for aneuploidy and during the process, the baby was found to have an absent nasal bone. Due to the difficulty in routinely obtaining a definitive assessment of the nasal bone, and its c...
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Thanks Kim at Emergiblog!
Thanks Kim for mentioning my recent post “The "Flu" and Pregnancy: Get Smart, Get Vaccinated NOW” in your weekly Emergiblog Grand Rounds. Honored to be included among the contributors and love your format. Tall Chocolate though, I'm not! Maybe a...
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Low PAPP-A in Presence of Low Risk for Fetal Aneuploidy
Below are comments from a woman aged 44 who is carrying a pregnancy conceived by in vitro fertilization (IVF) using a ‘donor egg’ from a 21 year old woman. She had combined first trimester screening done with composite results that were very reas...
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Diabetes in Pregnancy - 5 - Diagnosis of Gestational Diabetes
In our last post, we discussed the basic differences between type 1 and type 2 diabetes and concluded with the characterization of gestational diabetes mellitus (GDM), diabetes that is first expressed (or detected) as the result of pregnancy, as f...
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Chromosomal Abnormalities and Multiple Gestations - 3
To bring those of you just jumping into this discussion up to speed, in our last two regular posts on the subject of “Chromosomal Abnormalities in Multiple Gestations,” we presented a case in which a 40 year old woman, who conceived twins by IVF a...
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Reader's Questions Related to Low PAPP-A in First Trimester Screening for Aneuploidy
The following comments and questions were left on my previous post regarding Low Pregnancy-Associated Plasma Protein-A (PAPP-A) and Pregnancy Outcome. The questions are excellent and summarize the concerns of many of our readers who have a low PA...
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Cervical Incompetence and Cerclage - 5 - Cervical Assessment
Once the suspected diagnosis of cervical incompetence has been established, a decision has to be made regarding what therapy is offered to the patient. I have found that the patient’s participation in that decision is often very important. When ...
