-
Two First Trimester Miscarriages
First , I would like to apologize to all my readers and especially to those who left comments and were hoping for timely responses. I took a week's vacation at the beach and brought the computer with me to keep up with my blogging, but there was n...
-
Ethnic Differences in Components of First Trimester Screening for Aneupolidy
In our last post, we briefly discussed the use of fetal nasal bone (NB) assessment in first trimester screening for aneuploidy and mentioned in passing that ethnic differences have been described. The reader below was curious to find out if ethnic...
-
Absence of Fetal Nasal Bone in Midtrimester as a Marker for Down Syndrome
Tamsen has left a new comment on your post "Amniocentesis is Not Without Risk": I am 29 years old and am 21 weeks along. I just had an ultrasound a couple of days ago and was told that the nasal bone is not showing up which puts me at higher risk ...
-
Maternal Serum Screening in Midtrimester
Prenatal maternal serum screening in midtrimester (AFP, estriol, hCG, and inhibin-A) is without doubt the most misunderstood test routinely offered to women during pregnancy. Misconceptions and uncertainty abound on the parts of both patients and...
-
X-Linked Hydrocephalus - 1 - Introduction
Within the past year, we had the pleasure of seeing a young woman who was referred to us in early pregnancy with a strong family history of “X-linked hydrocephalus.” Indeed, she was known to be a carrier of a mutation in the cell adhesion molecul...
-
Thanks to Dr. Bongi for a New Year's Grand Rounds
Many thanks to Dr. Bongi at Other Things Amanzi for a most extraordinary and colorful Grand Rounds. All I can say is what a great way to start the new Year! Between the photographs of Africa and the selection of submissions, this is one Grand Rou...
-
Plasminogen Activator Inhibitor 1 (PAI 1) and Recurrent Pregnancy Loss
Back in June, a reader I.R. left a comment on my post "Recurrent Early Pregnancy Loss - 7 - Immunologic a...". Her specific question related to the possible role of plasminogen activator inhibitor 1 (PAI 1) activity and polymorphisms in recurrent...
-
Readers' Concerns Regarding Rh-immune Globulin and ABO-Incompatibilty
Anonymous said...Great information! I just miscarried and I want to know why. I am 0- and received a Rhogam shot at 28 weeks with my 1st child. I did not receive a shot after delivery--I checked my records. Did this (not receiving a shot) contribu...
-
Cytomegalovirus (CMV) Reprise
There is not a week that goes by in my practice that I do not have to address questions regarding cytomegalovirus (CMV) infections and pregnancy. Since we have also been discussing recurrent pregnancy loss in various contexts over the past year, ...
-
Grand Rounds 4.36 at Parallel Universes!
Many thanks to Parallel Universes for this week's rendition of Grand Rounds 4.36 and for including a link to my recent post on the Evaluation and Management of Polyhydramnios. The evaluation of amniotic fluid is an important part of every pregnanc...
