Why Chantix may reduce alcohol consumption.
But there is also some evidence from studies of experimental rats, which suggests that varenicline (Chantix) may have a more direct effect on alcohol consumption. Last year, Dr Pia Steenland and colleagues at University of California published a paper in the prestigious journal, “Proceedings of the National Academy of Sciences” Their study found that animals who became used to drinking ethanol (alcohol) and were then treated with varenicline showed reduced alcohol-seeking behavior, and reduced alcohol consumption, without having any effects on water or sugar consumption. The authors concluded that,
“The finding that varenicline decreased ethanol consumption in chronically exposed ethanol-consuming rats suggests that varenicline may serve as a therapeutic treatment to reduce alcohol consumption in alcoholic subjects; however, this remains to be examined.”
This means that these results in animals are suggestive of a potential effect in humans, but proper clinical trials in humans will be needed. So these reports of reduced interest in drinking alcohol among people taking Chantix for smoking cessation, may have a real pharmacological basis that may ultimately be clinically useful for people with alcohol problems.
The full study can be viewed at: