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Subjects Invited for Immersion Pulmonary Edema Study

Duke University contacted me regarding Swimming and Pulmonary Edema.

They are recruiting experimental subjects who have experienced immersion pulmonary edema to participate in studies to investigate causes of this condition. The studies concentrate on effects of cold-water facial and body immersion on pulmonary arterial pressure and pulmonary arterial wedge pressure. It will also analyze subjects' DNA to see if people who have experienced immersion pulmonary edema (IPE) may have a genetic predisposition.

DNA Analysis Study
Subjects over 18 years old who have experienced immersion pulmonary edema are needed to donate a small amount of blood for this DNA analysis. This will involve one blood draw and a review of past medical records. Subjects will be paid $50 for participation in this part of the study.

Immersion and Exercise Study
A small group of subjects will be studied more extensively to investigate the effect of cold water immersion on pulmonary arterial and pulmonary arterial wedge pressures. Subjects will exercise underwater on a cycle ergometer (bicycle) modified for use in a pool inside a hyperbaric chamber. Subjects will be monitored with arterial and pulmonary artery catheters.

Subjects must come to the laboratory about 3 hours before the immersion and exercise study for a physical exam, an exercise test, orientation, and scheduling for the experimental day. The experimental day (about 8 hours) takes place at least three days later.

Subjects involved in the immersion and exercise part of the study will be paid up to $350 for participation.

Subjects undergoing immersion and exercise must be 18-40 years of age, physically fit (regularly exercise at least twice a week), and have no physical impairment that would prevent them from participation.

Immersion Pulmonary Edema
Immersion pulmonary edema is a sudden accumulation of excessive fluid in the lung air spaces during swimming or diving. It is characterized by cough, shortness of breath, decreased blood oxygen levels, and coughing up blood. This condition has caused death. Its cause is unknown, but it can occur in swimmers and divers who are usually young and healthy, including military recruits. It may occur in swimmers or divers who have experienced similar conditions before without any problems.

To Participate Contact:
For more information, please contact Dionne Peacher at or 919-668-0001.

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Dr. Bookspan is an award-winning scientist whose goal is to make exercise easier and healthier.