Drugs A - Z

Ziv-Aflibercept Solution for injection

It works by slowing or stopping cancer cell growth

Generic Name: Zaltrap

What is this medicine?

ZIV-AFLIBERCEPT is a chemotherapy drug. It works by slowing or stopping cancer cell growth. It is used with other medicines to treat certain types of colon cancer.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

-bleeding disorders
-dehydration
-heart disease
-high blood pressure
-history of stomach bleeding
-history of stroke
-infection (especially a virus infection such as chickenpox, cold sores, or herpes)
-kidney disease
-low blood counts, like low white cell, platelet, or red cell counts
-recent surgery
-an unusual or allergic reaction to ziv-aflibercept, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

How should I use this medicine?

This medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.


Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

What if I miss a dose?

It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.

What may interact with this medicine?

Interactions are not expected.

What should I watch for while using this medicine?

Do not become pregnant while taking this medicine or for at least 3 months after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. Men should not father a child while taking this medicine and for 3 months after stopping it. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information.

Check with your doctor or health care professional if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.

You may need blood work done while you are taking this medicine.

In some patients, this medicine may cause a serious brain infection that may cause death. If you have any problems seeing, thinking, speaking, walking, or standing, tell your doctor right away. If you cannot reach your doctor, urgently seek other source of medical care.

Avoid taking products that contain aspirin, acetaminophen, ibuprofen, naproxen, or ketoprofen unless instructed by your doctor. These medicines may hide a fever.



Be careful brushing and flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this medicine.



Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.



This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.

Your condition will be monitored carefully while you are receiving this medicine.


Last Updated: September 26, 2012
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