• Basic Info
• Top Questions
• Clinical Info

What is this medicine?

ZIPRASIDONE (zi PRAY si done) is used to treat schizophrenia and bipolar disorder, also known as manic-depression.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• dementia
• diabetes or high blood sugar
• heart disease, including heart failure
• irregular heartbeat
• liver disease
• low potassium level in the blood
• Parkinson's disease or other movement disorders
• previous heart attack or stroke
• suicidal thoughts, plans, or attempt by you or a family member
• an unusual or allergic reaction to ziprasidone, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take with food. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on the advice of your doctor or health care professional.

A patient information sheet for the product will be given with each prescription and refill. Read this sheet carefully each time. The sheet may change frequently.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

• alfuzosin
• arsenic trioxide
• certain antidepressants
• certain macrolide antibiotics like clarithromycin, erythromycin, telithromycin, and troleandomycin
• certain quinolone antibiotics like gatifloxacin, grepafloxacin, levofloxacin, moxifloxacin, and sparfloxacin
• chloroquine
• cisapride
• clozapine
• dolasetron
• droperidol
• halofantrine
• haloperidol
• levomethadyl
• medicines for treating heart-rhythm problems like amiodarone, dofetilide, flecainide, procainamide, quinidine, and sotalol
• methadone
• palonosetron
• pentamidine
• phenothiazines like chlorpromazine, mesoridazine and thioridazine
• pimozide
• probucol
• propafenone
• risperidone
• sertindole
• tacrolimus
• vardenafil

This medicine may also interact with the following medications:

• carbamazepine
• diuretics
• medicines for fungal infections like fluconazole, itraconazole, ketoconazole, voriconazole
• medicines for Parkinson's disease
• some medications for high blood pressure
• stimulants like amphetamine, dextroamphetamine

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.